I-N-Acetylneuraminic acid umgubo uMvelisi Newgreen N-Acetylneuraminic acid Supplement
Ingcaciso yeMveliso
I-N-acetylneuraminic acid (i-NANA, i-Neu5Ac) iyinxalenye enkulu ye-glycoconjugates, njenge-glycolipids, i-glycoproteins, kunye ne-proteoglycans (sialoglycoproteins), enika uphawu lokubopha okukhethiweyo kwamacandelo e-glycosylated. I-Neu5Ac isetyenziselwa ukufunda i-biochemistry yayo, i-metabolism kunye nokuthatha kwi-vivo kunye ne-in vitro. I-Neu5Ac ingasetyenziselwa ukuphuhliswa kwee-nanocarriers.
I-COA
| Izinto | Iinkcukacha | Iziphumo | |
| Imbonakalo | Umgubo omhlophe | Umgubo omhlophe | |
| Isivavanyi |
| Dlula | |
| Ivumba | Akukho nanye | Akukho nanye | |
| Uxinaniso olungakhululekanga (g/ml) | ≥0.2 | 0.26 | |
| Ilahleko ekomisweni | ≤8.0% | 4.51% | |
| Intsalela kwi-Ignition | ≤2.0% | 0.32% | |
| PH | 5.0-7.5 | 6.3 | |
| I-avareji yobunzima bemolekyuli | <1000 | 890 | |
| Iintsimbi ezinzima(Pb) | ≤1PPM | Dlula | |
| As | ≤0.5PPM | Dlula | |
| Hg | ≤1PPM | Dlula | |
| Ubalo lwebhaktiriya | ≤1000cfu/g | Dlula | |
| IColon Bacillus | ≤30MPN/100g | Dlula | |
| Igwele kunye noMngundo | ≤50cfu/g | Dlula | |
| Intsholongwane ye-Pathogenic | Ibi | Ibi | |
| Ukuqukumbela | Ukuhambelana neenkcukacha | ||
| Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo | ||
Umsebenzi
1. Ukuphucula ubukrelekrele kunye nenkumbulo yomntwana
I-N-Acetylneuraminic acid sisakhiwo esibalulekileyo se-gangliosides kwingqondo. Umxholo we-asilic acid kwi-nerve cell membrane uphindwe kayi-20 kunezinye iiseli. Ngenxa yokuba ukuhanjiswa kolwazi lwengqondo kunye nokuqhutyelwa kweempembelelo ze-nerve kufuneka kuphunyezwe ngokusebenzisa i-synapses, kwaye i-N-Acetylneuraminic acid isondlo sobuchopho esisebenza kwi-brain cell membranes kunye ne-synapses, ngoko i-N-Acetylneuraminic acid inokukhuthaza Ukuphuhliswa kwememori kunye nobukrelekrele. Uphononongo lufumanise ukuba ukonyusa umxholo we-N-Acetylneuraminic acid ekutyeni kokuncancisa kuya kwandisa umxholo we-N-Acetylneuraminic acid ebuchotsheni bomntwana, kwaye inqanaba lokuthetha lemizila yemfuza enxulumene nokufunda nalo liya kwanda, ngaloo ndlela liphucula amandla okufunda kunye nokukhumbula. Kwiintsana, umxholo we-N-Acetylneuraminic acid yi-25% kuphela yobisi lwebele.
2. I-Anti-senile dementia
I-N-Acetylneuraminic acid inefuthe lokukhusela kunye nokuzinza kwiiseli ze-nerve. Emva kokuba i-protease ibekwe kumphezulu we-nerve cell membrane idityaniswe ne-N-Acetylneuraminic acid, ayinakuthotywa yi-extracellular protease. Ezinye izifo ze-neurological, ezifana ne-senile dementia kunye ne-schizophrenia, ziya kunciphisa umxholo we-N-Acetylneuraminic acid egazini okanye ebuchosheni, kwaye emva kokubuyiselwa kunyango lweziyobisi, umxholo we-N-Acetylneuraminic acid uya kubuyela kwinto eqhelekileyo, ebonisa ukuba i-N-Acetylneuraminic acid ithatha inxaxheba. kwinkqubo yemetabolism yeeseli zemithambo-luvo .
3. Ukuchasana nokuqatshelwa
Phakathi kweemolekyuli kunye neeseli, phakathi kweeseli kunye neeseli, naphakathi kweeseli kunye nehlabathi langaphandle, i-N-Acetylneuraminic acid ekupheleni kwekhonkco leswekile inokusebenza njengendawo yokuqaphela okanye imaski indawo yokuqaphela. I-N-Acetylneuraminic acid edityaniswe ekupheleni kwe-glycosides ngokusebenzisa iibhondi ze-glycosidic inokuthintela ngokufanelekileyo ezinye iindawo ezibalulekileyo ze-antigenic kunye namanqaku okuqaphela kwi-cell surface, ngaloo ndlela ikhusela ezi saccharides ukuba ziqatshelwe kwaye zithotywe yi-immune system ejikelezayo.
Usetyenziso
1. I-N-Acetylneuraminic acid isetyenziselwa ukuveliswa kwee-neuraminidase inhibitors ezahlukeneyo, i-glycolipids kunye nezinye iimveliso ze-bioactive ezenziwe ngokwenziwa. Ingasetyenziswa njengesongezelelo sesondlo.
2. I-N-Acetylneuraminic acid idlala indima ebalulekileyo kwisondlo sokutya njenge-glyconutrient. Ilawula i-protein ye-half-life, i-acidification, i-neutralization yee-toxins ezahlukeneyo, i-cell adhesion kunye nokukhusela i-glycoprotein lysis. Ingasetyenziswa njengesongezo sokutya.
3. I-N-Acetylneuraminic acid ingasetyenziswa njenge-reagent yokuqala yokudibanisa i-biochemical derivatives yamachiza. Ingasetyenziswa njengento yokuthambisa.
Ukupakishwa kunye nokuhanjiswa
