INewgreen Supply Pharmaceutical 99% Purity Metallothionein Powder Material Metallothionein Mt Rabbit Liver Zinc Metallothionein
Ingcaciso yeMveliso
I-Metallothionein yiprotheni ephantsi yobunzima bemolekyuli enekhono lokubopha isinyithi kunye neempawu eziphezulu zokungeniswa. [1] Iipeptide ezimfutshane zizityebi kwi-cysteine kunye nobudlelwane obuphezulu kwiindidi zesinyithi esinzima. Yiprotheyini enobunzima obuphantsi bemolekyuli kunye nomxholo ophezulu kakhulu weentsalela ze-cysteine kunye neentsimbi. Iintsimbi ezidityanisiweyo ikakhulu ziyi-cadmium, ubhedu kunye ne-zinc, ezikhoyo ngokubanzi kwizinto eziphilayo ukusuka kwi-microorganisms ukuya ebantwini, kwaye isakhiwo sazo sigcinwe kakhulu.
I-COA
| IZINTO | UMGANGATHO | ISIPHUMO SOVAVANYO |
| Isivavanyi | 98%min Metallothionein | Iyahambelana |
| Umbala | Umgubo oMhlophe | Iyahambelana |
| Ivumba | Akukho vumba likhethekileyo | Iyahambelana |
| Ubungakanani besuntswana | I-100% iphumelele i-80mesh | Iyahambelana |
| Ilahleko ekomisweni | ≤5.0% | 2.35% |
| Intsalela | ≤1.0% | Iyahambelana |
| Intsimbi enzima | ≤10.0ppm | 7ppm |
| As | ≤2.0ppm | Iyahambelana |
| Pb | ≤2.0ppm | Iyahambelana |
| Intsalela yesitshabalalisi | Ibi | Ibi |
| Ubalo lweepleyiti lulonke | ≤100cfu/g | Iyahambelana |
| Igwele kunye noMngundo | ≤100cfu/g | Iyahambelana |
| E.Coli | Ibi | Ibi |
| Salmonella | Ibi | Ibi |
| Ukuqukumbela | Qhagamshelana neNgcaciso | |
| Ugcino | Igcinwe kwindawo epholileyo kunye neyomileyo, zigcine kude nokukhanya okuqinileyo kunye nobushushu | |
| Beka ubomi kwishelufa | Iminyaka emi-2 xa igcinwe ngokufanelekileyo | |
Umsebenzi
I-MT yiprotheni ebophelelayo yesinyithi ecebileyo kwi-cysteine. Iqela layo le-sulfhydryl linokuthi litshise ngamandla isinyithi esinetyhefu kwaye lizikhuphe emzimbeni, ngaloo ndlela liphumeza ukukhutshwa kwetyhefu. [4] I-MT inxulumene ne-metabolism ye-trace metals. Kuzo zonke izicubu ze-mammalian, i-MT-1 kunye ne-MT-2 ibonakaliswe nge-synergistically. I-MT-3 lilungu elithile lengqondo kule ntsapho. Iyakwazi ukubopha i-zinc kunye nobhedu kwaye inemisebenzi ebalulekileyo ye-neurophysiological kunye neuromodulation. Uphononongo kwizinto ezininzi eziphilayo zasemanzini zibonise ukuba i-MT idlala indima ebalulekileyo ekulawuleni izinto ezisisiseko zetsimbi, kwaye ineempembelelo ezithintelayo kunye ne-detoxifying kwizinto ezingezona ezisisiseko zetsimbi. I-MT inokunciphisa ngokufanelekileyo ubutyhefu besinyithi esinzima emzimbeni ngokudibanisa nesinyithi esinzima, kwaye okwangoku yeyona nto ifanelekileyo ye-biological chelating antidote ekusebenzeni kwezonyango.
Ukhuseleko lokusingqongileyo
Ukusebenzisa iimpawu zokudibanisa i-MT kunye nesinyithi, kunokwenzeka ukuzala okanye ukusebenzisa ubunjineli bezofuzo ukuseka inkqubo ye-MT ephezulu yokubonisa ukulawula ukungcola kwensimbi enzima. Ngokweengxelo, icuba ethanjiswe ngegwele le-MT gene inokunyusa kakhulu ukufunxa kwe-cu2 kumhlaba ongcolileyo, kwaye le ndlela ingasetyenziselwa ukulungisa iindawo ezingcoliswe zisinyithi ezinzima.
MT kunye nokumelana nemitha
I-ionizing radiation inokuvelisa inani elikhulu lama-radicals asimahla, anokonakalisa izinto eziphilayo ngokuthe ngqo okanye ngokungathanga ngqo. Uphononongo lubonise ukuba ukulawulwa komlomo we-MT kunokwandisa ixesha lokusinda kweempuku ezivezwe kwi-radiation ephezulu ye-ionizing, kunye nokunciphisa umonakalo kwi-immune system ebangelwa yi-dose ephezulu kunye ne-multiple low-dose ionizing radiation. . I-Oral MT inokuthatha inani elikhulu leCys engena emzimbeni. Ibonelela ngemathiriyeli ekrwada yokulungisa iibhondi ze-disulfide ezaphulwa yimitha emzimbeni.
Isifo seMT kunye neParkison (PD).
Uvavanyo oluninzi luye lwabonisa ukuba i-MT inefuthe elikhuselayo kwinkqubo ye-nervous. Iimvavanyo zibonise ukuba kwiigundane ze-transgenic, ukugqithisa kwe-MT-1 kunokutshintsha iimpawu ze-encephalitis kunye nokukhuthaza ukulungiswa kwengqondo. Yinto ekhuselayo kwiiseli zemithambo-luvo. Ngokufunda imodeli yokugwaza iigundane kunye nemodeli ye-ischemia, kufunyenwe ukuba i-MT-3 ibandakanyeka ekulungiseni umonakalo wenkqubo ye-nervous central. Isifo se-PD sibangelwa ukufakwa kwe-radicals yamahhala nge-6-hydroxydopamine, kunye ne-inducers ethile ye-MT isoforms engqondweni, njengoxinzelelo lwe-oxidative, i-cytokines kunye neenkqubo zokuvuvukala, inokuthintela le neurotoxicity, ekhululekile kwi-MT clearance Base ehlobene.
Usetyenziso
I-Metallothionein (MT) luhlobo lweprotheni ephantsi yemolekyuli etyebileyo kwi-cysteine kunye nesinyithi. Ngenxa yokukwazi ukubopha inani elikhulu le-ion zetsimbi kunye nomsebenzi walo okhethekileyo we-physiological, ihlawulwe ingqwalasela ngakumbi kwintsimi ye-biochemistry. Imbali yophando ye-MT ibe ngaphezu kweminyaka eyi-40, kwaye uphando malunga nesakhiwo sayo, iimpawu, ukulawulwa kofuzo kunye nomsebenzi we-biological uye wanda ngokunzulu. Amathuba okusetyenziswa kweMT abanzi kakhulu, kubandakanywa kodwa angaphelelanga koku:
1. Intsimi yezoNyango : I-MT isetyenziswa ikakhulu kwi-cardiovascular and cerebrovascular disease and tumors, kodwa ayizange isetyenziswe kwi-epilepsy.
2. Impilo yokutya kunye ne-cosmetic additive : I-MT inokusetyenziswa njengesongezo ekutyeni, izongezo zezempilo kunye nezithambiso ukunika izibonelelo zempilo ezongezelelweyo.
3. I-reagent ye-Genetic engineering : Kubunjineli bemfuza, iMT isetyenziswa njengesixhobo sokukhuthaza uphando kunye nokusetyenziswa kobunjineli bemfuzo.
4. Ukukhuselwa kweekhemikhali kunye nokusingqongileyo : I-MT isetyenziswa nakwiindawo zokukhusela iikhemikhali kunye nokusingqongileyo, umzekelo ukususa isinyithi esiyingozi.
amanqaku elabhoratri yezolimo : I-MT ingasetyenziswa njengenqaku lovavanyo kwiimvavanyo zezolimo, ngakumbi kuphononongo lokungcoliseka kwesinyithi esinzima kunye nokunyamezela izityalo kwiintsimbi ezinzima.
5. Ukongezelela, i-MT inomsebenzi wokuthatha inxaxheba ekugcinweni, ukuthutha kunye ne-metabolism yezinto ezilandelwayo ze-zinc kunye nobhedu, i-detoxification yezinto ezinzima ze-cadmium, i-mercury kunye ne-lead, i-radiation echasayo ye-ionizing kunye nokususa amaqela angenayo i-hydroxyl. Izakhi zofuzo ze-MT zendalo ziye zenziwa kwicuba, i-petunia kunye nezinye izityalo ngobunjineli bezofuzo, kwaye izityalo ze-transgenic zibonise ukuchasana okuphezulu kungcoliseko lwe-cadmium. Ukuba i-MT gene idluliselwa kwi-clover kunye ne-duckweed kwaye ityalwe emhlabeni okanye emanzini angcoliswe yi-cadmium kunye ne-mercury, inokufunxa inani elikhulu lesinyithi esinetyhefu emhlabeni nasemanzini, kwaye idlale indima ekususeni isinyithi esiyingozi.
Iimveliso ezinxulumeneyo:
Umzi-mveliso omtsha oluhlaza ukwabonelela ngeeAmino acids ngolu hlobo lulandelayo:
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