Yintoni iAzelaic Acid?
I-Azelaic Acid yindalo ye-dicarboxylic acid esetyenziswa kakhulu kukhathalelo lolusu kunye nokunyanga iimeko ezahlukeneyo zolusu. Ine-antibacterial, anti-inflammatory kunye ne-keratin elawula iipropati kwaye isoloko isetyenziselwa ukunyanga iingxaki zesikhumba ezifana ne-acne, i-rosacea kunye ne-hyperpigmentation.
IiPropati zoMzi kunye nezeMichiza yeAzelaic Acid
1. Ulwakhiwo lweMichiza kunye neePropati
Ulwakhiwo lweMichiza
Igama leKhemikhali: Azelaic Acid
Ifomula yeMichiza: C9H16O4
Ubunzima beMolekyuli: 188.22 g / mol
Ulwakhiwo: Iasidi yeAzelaic yidityana ethe tye egcwele idicarboxylic acid.
2.Iimpahla zePhysical
Imbonakalo: Iasidi yeAzelaic ibonakala ngathi ngumgubo omhlophe wekristale.
Ukunyibilika: Inyibilika kancinane emanzini kodwa inyibilika ngakumbi kwizinyibilikisi zendalo ezifana ne-ethanol kunye nepropylene glycol.
Indawo yokunyibilika: Ngokumalunga ne-106-108 ° C (223-226 ° F).
3. Indlela yokwenza
I-Antibacterial: I-Azelaic acid inqanda ukukhula kweebhaktheriya, ngakumbi i-Propionibacterium acnes, eyona nto inegalelo elikhulu kwi-acne.
I-Anti-Inflammatory: Inciphisa ukuvuvukala ngokuthintela ukuveliswa kwe-cytokines e-pro-inflammatory.
I-Keratinization Regulation: I-Azelaic acid inceda ukuqhelanisa ukuchithwa kweeseli zesikhumba ezifileyo, ukuthintela ii-pores ezivaliweyo kunye nokwakhiwa kwee-comedones.
I-Tyrosinase Inhibition: Ivimbela i-enzyme ye-tyrosinase, ebandakanyeka kwimveliso ye-melanin, ngaloo ndlela inceda ukunciphisa i-hyperpigmentation kunye ne-melasma.
Ziziphi iiNzuzo zeAzelaic Acid?
I-Azelaic Acid yi-dicarboxylic acid eguquguqukayo esetyenziswa kakhulu kukhathalelo lolusu kunye nonyango lweengxaki zolusu ezahlukeneyo. Nazi iingenelo eziphambili ze-azelaic acid:
1. Nyanga i-Acne
- Impembelelo ye-Antibacterial: I-Azelaic acid inokuthintela ngokufanelekileyo ukukhula kwe-Propionibacterium acnes kunye ne-Staphylococcus aureus, eyona bhaktheriya ye-pathogenic ye-acne.
- I-Anti-inflammatory effect: Inokunciphisa impendulo yokuvuvukala kwesikhumba kwaye ikhulule ubomvu, ukuvuvukala kunye nentlungu.
- I-Keratin Ukulawula: I-Azelaic acid inceda ukuqhelanisa ukuchithwa kweeseli zesikhumba ezifileyo, ukuthintela ii-pores ezivaliweyo kunye nokwakheka kwamabala.
2. Unyango lweRosacea
- Nciphisa uBubomvu: I-Azelaic acid inciphisa ngokufanelekileyo ubomvu kunye nokuvuvukala okuhambelana ne-rosacea.
- Impembelelo ye-Antibacterial: Ivimbela ukukhula kwebhaktheriya enxulumene ne-rosacea kwaye inciphisa umngcipheko wosulelo lwesikhumba.
3. Ukuphucula umbala
- I-Whitening effect: I-Azelaic acid inceda ukunciphisa i-pigmentation kunye ne-chloasma ngokuvimbela umsebenzi we-tyrosinase kunye nokunciphisa ukuveliswa kwe-melanin.
-Nokuba ithoni yolusu: Ukusetyenziswa rhoqo kukhokelela kwithoni yesikhumba ngakumbi, ukunciphisa amabala amnyama kunye nokungalingani kwebala.
4. Isiphumo se-Antioxidant
-I-Neutralizing Free Radicals: I-Azelaic acid ineepropathi ze-antioxidant ezenza i-radicals yamahhala kwaye inciphise umonakalo woxinzelelo lwe-oxidative eluswini.
- I-Anti-Aging: Ngokunciphisa umonakalo omkhulu wamahhala, i-Azelaic acid inceda ukuguga kwesikhumba kunye nokunciphisa ukubonakala kwemigca emihle kunye nemibimbi.
5. Unyango lwe-Post-Inflammatory Pigmentation (PIH)
- Nciphisa i-Pigmentation: I-Azelaic acid iphatha ngokufanelekileyo i-post-inflammatory hyperpigmentation, ehlala ivela emva kwe-acne okanye ezinye iimeko zesikhumba ezivuthayo.
- Ukukhuthaza ukulungiswa kolusu: Ikhuthaza ukuvuselelwa kunye nokulungiswa kweeseli zesikhumba kunye nokukhawulezisa ukucima kwe-pigmentation.
6. Ifanele ulusu olubuthathaka
- Ithambile kwaye ayicaphukisi: I-Azelaic acid inyamezeleka kakuhle kwaye ifanelekile kwiintlobo zesikhumba ezinobuthathaka.
- I-Noncomedogenic: Ayifaki i-pores kwaye ifanelekile kwi-acne-prone skin.
7. Nyanga ezinye izifo zolusu
- I-Keratosis Pilaris: I-Azelaic acid inokunceda ukunciphisa i-rough, isikhumba esiphakanyisiweyo esihambelana ne-Keratosis Pilaris.
- Ezinye izifo zesikhumba ezivuthayo: Ikwanazo iziphumo ezithile zonyango kwezinye izifo zesikhumba ezivuthayo ezifana ne-eczema kunye ne-psoriasis.
Zithini Izicelo ZeAzelaic Acid?
1. Nyanga i-Acne: Amalungiselelo asemxholweni
- I-acne Creams kunye ne-Gels: I-Azelaic acid isetyenziswa ngokuqhelekileyo kumalungiselelo e-topical ukunyanga i-acne epholileyo ukuya ephakathi. Inceda ukunciphisa inani lezilonda ze-acne kunye nokuthintela ukubunjwa kwamatsha.
- Unyango oludityanisiweyo: Ihlala isetyenziswa kunye nolunye unyango lwe-acne olufana ne-benzoyl peroxide okanye i-retinoic acid ukuphucula ukusebenza.
2. Unyango lweRosacea: Amalungiselelo okulwa nokuvuvukala
- I-Rosacea Creams kunye neGel: I-Azelaic acid iyanciphisa ngokufanelekileyo ubomvu kunye nokuvuvukala okuhambelana ne-rosacea kwaye isoloko isetyenziselwa ukulungiswa kwezihloko ezijoliswe ngokukodwa kwi-rosacea.
- Ulawulo Lwexesha elide: Ilungele ulawulo lwexesha elide lwe-rosacea, inceda ukugcina imeko ezinzileyo yesikhumba.
3. Ukuphucula umbala: Iimveliso ezimhlophe
- Ukukhanya kweCreams kunye neSerums: I-Azelaic acid inceda ukunciphisa i-pigmentation kunye ne-melasma ngokuvimbela umsebenzi we-tyrosinase kunye nokunciphisa ukuveliswa kwe-melanin.
-Nokuba ithoni yolusu: Ukusetyenziswa rhoqo kukhokelela kwithoni yesikhumba ngakumbi, ukunciphisa amabala amnyama kunye nokungalingani kwebala.
4. I-Antioxidant kunye ne-anti-aging: Imveliso yokunyamekela ulusu lwe-Antioxidants
- I-Anti-Aging Creams kunye neSerums: Iimpawu ze-antioxidant ze-Azelaic acid zenza ukuba ibe yinto ebalulekileyo kwiimveliso zokunakekelwa kwesikhumba ezichasayo, ezinceda ukunciphisa umonakalo we-radical wamahhala kwesikhumba kunye nokunciphisa ukuguga kwesikhumba.
- Ukunyamekelwa kolusu lwemihla ngemihla: Kufanelekile ukunakekelwa kwesikhumba imihla ngemihla, ukubonelela ngokhuseleko lwe-antioxidant kunye nokugcina ulusu lusempilweni.
5. Unyango lwe-Post-Inflammatory Pigmentation (PIH): Iimveliso zokulungisa iPigmentation
- Ukulungisa iiCreams kunye neeSerums: I-Azelaic acid iyasebenza ekuphatheni i-post-inflammatory hyperpigmentation kwaye isoloko isetyenziselwa ukulungiswa kwe-creams kunye ne-serums ukunceda ukukhawuleza ukulahleka kwe-hyperpigmentation.
- Ukulungiswa kolusu: Khuthaza ukuvuselelwa kunye nokulungiswa kweeseli zolusu kunye nokukhawulezisa ukubuna kombala.
6. Nyanga ezinye izifo zolusu
Keratosis pilaris
-Imveliso ye-keratin conditioning: I-Azelaic acid inokunceda ukunciphisa i-rough, ephakanyisiweyo yesikhumba ehambelana ne-keratosis pilaris kwaye isoloko isetyenziswa kwiimveliso ze-keratin.
- Ukuthambisa ulusu: Ukukhuthaza ukuguda kwesikhumba kunye nokuthamba, ukuphucula ukumila kolusu.
Ezinye izifo zesikhumba ezivuthayo
- I-Eczema kunye ne-Psoriasis: I-Azelaic acid nayo ineempembelelo ezithile zonyango kwezinye izifo zesikhumba ezivuthayo ezifana ne-eczema kunye ne-psoriasis, kwaye isetyenziswa rhoqo kumalungiselelo ahambelanayo.
7. Ukunyamekela kwe-scalp: I-Anti-Inflammatory and Antibacterial Products
- Iimveliso zokunakekelwa kwe-scalp: I-Azelaic acid ye-anti-inflammatory kunye ne-antibacterial properties yenza ukuba ilungele ukusetyenziswa kwiimveliso zokunakekelwa kwe-scalp ukunceda ukunciphisa ukuvuvukala kwe-scalp kunye nokusuleleka.
- Impilo ye-scalp: Ikhuthaza impilo ye-scalp kwaye inciphisa inkwethu kunye nokurhawuzelelwa.
Imibuzo eNxulumeneyo onokuthi ubenomdla kuyo:
Ngabai-azelaic acidzineziphumo ebezingalindelekanga?
I-Azelaic acid inokuba nemiphumo emibi, nangona ngokuqhelekileyo inyamezeleke kakuhle ngabantu abaninzi. Iziphumo ebezingalindelekanga zihlala zithambile kwaye zithande ukuncipha ngokuqhubeka kokusetyenziswa. Nazi ezinye iziphumo ebezingalindelekanga kunye nokuqwalaselwa:
1. Iimpembelelo eziPhakamileyo
Ukucaphuka kolusu
- Iimpawu: Ukucaphuka kancinci, ububomvu, ukurhawuzelelwa, okanye imvakalelo evuthayo kwindawo yesicelo.
- Ulawulo: Ezi mpawu zihlala ziphela njengoko ulusu lwakho luziqhelanisa nonyango. Ukuba ukucaphuka kuyaqhubeka, unokufuna ukunciphisa ukuphindaphinda kwesicelo okanye udibane nomboneleli wezempilo.
Ukomisa kunye nokuQweba
- Iimpawu: Ukomisa, ukugqabhuka, okanye ukuxobuka kolusu.
- Ulawulo: Sebenzisa i-moisturizer ethambileyo ukunciphisa ukomisa kunye nokugcina ukumanzisa kwesikhumba.
2. Iimpembelelo eziPhakamileyo eziNcinci
Iimpendulo ze-hypersensitivity
Iimpawu: Ukurhawuzelelwa kakhulu, irhashalala, ukudumba, okanye ukurhawuzelela.
- Ulawulo: Yeka ukusebenzisa ngokukhawuleza kwaye udibane nomboneleli wezempilo ukuba ufumana naziphi na iimpawu zokungaphenduli.
Ukwandiswa koBuvakalelo beLanga
- Iimpawu: Ukonyuka kobuntununtunu ekukhanyeni kwelanga, okukhokelela ekutshisweni lilanga okanye ukonakala kwelanga.
- Ulawulo: Sebenzisa isikhuselo-langa esibanzi esibanzi yonke imihla kwaye uthintele ukuba sesichengeni selanga ixesha elide.
3. Iziphumo ezingalindelekanga ezinqabileyo
Iimpendulo eziMandundu zolusu
- Iimpawu: Ububomvu obugqithisileyo, amadyunguza, okanye ukuxobuka kakhulu.
- Ulawulo: Yeka ukusebenzisa kwaye ufune iingcebiso zonyango ukuba ufumana naluphi na ukusabela okubukhali kwesikhumba.
4. Izilumkiso kunye neeNgqwalasela
Uvavanyo lwePatch
Isincomo: Ngaphambi kokusebenzisa i-azelaic acid, yenza uvavanyo lwe-patch kwindawo encinci yesikhumba ukujonga nakuphi na ukusabela okungalunganga.
Intshayelelo ngokuthe ngcembe
Isincomo: Ukuba umtsha kwi-azelaic acid, qala ngokugxininiswa okusezantsi kwaye ngokuthe ngcembe wandise ukuphindaphindeka kwesicelo ukuvumela ulusu lwakho ukuba lulungelelanise.
Uthethwano
- Isincomo: Dibana nogqirha wesikhumba okanye umboneleli wezempilo phambi kokuba uqale i-azelaic acid, ngakumbi ukuba unolusu olubuthathaka okanye usebenzisa ezinye izithako ezisebenzayo zokhathalelo lwesikhumba.
5. Abemi abakhethekileyo
Ukukhulelwa nokuncancisa
- Ukhuseleko: I-Azelaic acid ngokuqhelekileyo ithathwa njengekhuselekile ukusetyenziswa ngexesha lokukhulelwa kunye nokuncelisa, kodwa kusoloko kulungele ukubonisana nomboneleli wezempilo ngaphambi kokuba uqale naluphi na unyango olutsha.
Ulusu olunovakalelo
-Uqwalaselo: Abantu abanolusu olubuthathaka kufuneka basebenzise i-azelaic acid ngononophelo kwaye banokuzuza kwimixube eyilelwe ulusu olubuthathaka.
Kuthatha ixesha elingakanani ukubona iziphumo zei-azelaic acid?
Ixesha elithathayo ukubona iziphumo ezivela kwi-azelaic acid inokwahluka, kodwa uphuculo lokuqala luhlala lubonwa kwiiveki ezi-2 ukuya kwezi-4 ze-acne, iiveki ezi-4 ukuya kwezi-6 ze-rosacea, kunye ne-4 ukuya kwiiveki ze-8 ze-hyperpigmentation kunye ne-melasma. Iziphumo ezibaluleke ngakumbi zenzeka emva kwe-8 ukuya kwiiveki ze-12 zokusetyenziswa rhoqo. Izinto ezifana nokuxinana kwe-azelaic acid, ukusetyenziswa rhoqo, iimpawu zolusu lomntu ngamnye, kunye nobukhulu bemeko ephathwayo inokuchaphazela ukusebenza kunye nesantya seziphumo. Ukusetyenziswa rhoqo kunye nokungaguquguqukiyo, kunye neendlela ezihambelanayo zokunakekelwa kwesikhumba, kunokunceda ukufezekisa iziphumo ezilungileyo.
Imiba enefuthe kwiziphumo
Ukugxilwa kweAzelaic Acid
Ugxininiso oluPhezulu: Iimveliso ezinoxinzelelo oluphezulu lwe-azelaic acid (umzekelo, i-15% ukuya kwi-20%) zinokuvelisa iziphumo ezikhawulezayo nezibonakalayo.
Uxinzelelo olusezantsi: Iimveliso ezinoxinzelelo olusezantsi zingathatha ixesha elide ukubonisa iziphumo ezibonakalayo.
Ukuphindaphinda kosetyenziso
Ukusetyenziswa okungaguqukiyo: Ukusebenzisa i-azelaic acid njengoko kuyalelwe, ngokuqhelekileyo kube kanye okanye kabini yonke imihla, kunokuphucula ukusebenza kunye nokukhawulezisa iziphumo.
Ukusetyenziswa okungahambelaniyo: Ukusetyenziswa okungaqhelekanga kunokulibazisa iziphumo ezibonakalayo kunye nokunciphisa ukusebenza kakuhle.
Iimpawu zolusu lomntu ngamnye
Uhlobo lwesikhumba: Uhlobo lwesikhumba lomntu kunye nemeko inokuchaphazela ukuba iziphumo zibonwa ngokukhawuleza kangakanani. Umzekelo, abantu abanolusu olukhaphukhaphu banokubona iziphumo ngokukhawuleza xa kuthelekiswa nabo banolusu olumnyama.
Ubungqongqo bemeko: Ubunzima bemeko yolusu oluphathwayo bunokuchaphazela ixesha elithathayo ukubona iziphumo. Iimeko ezithambileyo zinokuphendula ngokukhawuleza kuneemeko ezinzima kakhulu.
Usebenzisa nini i-azelaic acid, kusasa okanye ebusuku?
I-Azelaic acid ingasetyenziswa kokubini kusasa nasebusuku, kuxhomekeke kwindlela yakho yokhathalelo lwesikhumba kunye neemfuno ezithile. Ukuba isetyenziswe kusasa, soloko ulandela nge-sunscreen ukukhusela ulusu lwakho kumonakalo we-UV. Ukuyisebenzisa ebusuku kunokuphucula ukulungiswa kwesikhumba kunye nokunciphisa ukusebenzisana nezinye izithako ezisebenzayo. Ukufumana izibonelelo eziphezulu, abanye abantu bakhetha ukusebenzisa i-azelaic acid kusasa nasebusuku, kodwa kubalulekile ukujonga impendulo yolusu lwakho kwaye uhlengahlengise ngokufanelekileyo. Hlala usebenzisa i-azelaic acid emva kokuhlanjululwa nangaphambi kokuba ufume, kwaye ucinge ukuba ingena njani kwirejimeni yakho yokunakekelwa kwesikhumba ukuze ufumane iziphumo ezilungileyo.
Yintoni ongaxutywanga nayoi-azelaic acid?
I-Azelaic acid sisithako esiguquguqukayo kwaye sinyamezeleke ngokufanelekileyo, kodwa kubalulekile ukuba ukhumbule indlela edibana ngayo nezinye izithako ezisebenzayo kwindlela yakho yokhathalelo lwesikhumba. Ukuxuba izithako ezithile kunokukhokelela ekucaphukeni, ukunciphisa ukusebenza kakuhle, okanye ezinye iziphumo ezingafunekiyo. Nazi ezinye izikhokelo malunga nokuba ungaxubani ne-azelaic acid:
1. IiExfoliants ezinamandla
IAlpha Hydroxy Acids (AHAs)
- Imizekelo: I-Glycolic acid, i-lactic acid, i-mandelic acid.
- Isizathu: Ukudibanisa i-azelaic acid kunye ne-AHAs eqinile inokunyusa umngcipheko wokucaphuka, ubomvu, kunye nokukhupha. Zombini zi-exfoliants, kwaye ukuzisebenzisa kunye kunokuba nzima kakhulu kulusu.
IBeta Hydroxy Acids (BHAs)
- Imizekelo: Salicylic acid.
- Isizathu: Ngokufana nee-AHA, ii-BHA nazo zi-exfoliants. Ukuzisebenzisa ngokubambisana ne-azelaic acid kunokukhokelela ekugqithiseni ngokugqithiseleyo kunye nokukhathazeka kwesikhumba.
2. IiRetinoids
- Imizekelo: Retinol, Retinaldehyde, Tretinoin, Adapalene.
- Isizathu: I-Retinoids yizithako ezinamandla ezinokubangela ukomisa, ukukhupha, kunye nokucaphuka, ngakumbi xa kuqalwa kuqala. Ukudibanisa kunye ne-azelaic acid kunokunyusa le miphumo emibi.
3. I-Benzoyl Peroxide
Isizathu
- Ukucaphuka: I-Benzoyl peroxide yinto eqinile yokulwa ne-acne enokubangela ukomisa nokucaphuka. Ukuyisebenzisa kunye ne-azelaic acid kunokunyusa umngcipheko wokucaphuka kwesikhumba.
- UkuNcitshiswa kokuSebenza: I-Benzoyl peroxide inokuthi idibanise nezinye izithako ezisebenzayo, ezinokunciphisa ukusebenza kwazo.
4. IVithamin C (Ascorbic Acid)
Isizathu
- Amanqanaba e-pH: I-Vitamin C (i-ascorbic acid) idinga i-pH ephantsi ukuba isebenze, ngelixa i-azelaic acid isebenza kakuhle kwi-pH ephezulu. Ukuzisebenzisa kunye kunokuphazamisa ukusebenza kwazo zombini izithako.
- Ukucaphuka: Ukudibanisa ezi zimbini izithako ezinamandla kunokunyusa umngcipheko wokucaphuka, ngakumbi kwisikhumba esibucayi.
5. Niacinamide
Isizathu
- Ukusebenzisana okunokwenzeka: Ngelixa i-niacinamide inyamezeleka ngokubanzi kwaye inokusetyenziswa kunye nezithako ezininzi ezisebenzayo, abanye abantu banokufumana ukucaphuka xa beyidibanisa ne-azelaic acid. Lo ayingomthetho wendalo yonke, kodwa yinto ekufuneka uyiqaphele.
6. Eminye Imisebenzi Enamandla
Imizekelo
- IHydroquinone, i-Kojic Acid, kunye nezinye izinto ezikhanyisa ulusu.
- Isizathu: Ukudibanisa izinto ezininzi ezisebenzayo ezijolise ekunyangeni i-hyperpigmentation kunokunyusa umngcipheko wokucaphuka kwaye akunakunyusa ukusebenza kakuhle.
Indlela yokudibanisaAzelaic AcidNgokukhuselekileyo:
Enye i-Use
-Iqhinga: Ukuba ufuna ukusebenzisa iazelaic acid ecaleni kwezinye izinto ezinamandla, cinga ngokutshintsha ukusetyenziswa kwazo. Ngokomzekelo, sebenzisa i-azelaic acid ekuseni kunye ne-retinoids okanye i-AHAs / BHAs ebusuku.
Uvavanyo lwePatch
- Isincomo: Soloko usenza uvavanyo lwepetshi xa usazisa isithako esitsha esisebenzayo kwindlela yakho ukukhangela naziphi na iziphumo ezibi.
Qala ngokucotha
-Iqhinga: Yazisa i-azelaic acid ngokuthe ngcembe, ukuqala ngoxinzelelo olusezantsi kunye nokwandisa ubuninzi njengoko ulusu lwakho lusakha ukunyamezelana.
Dibana noGqirha weDermatologist
- Isincomo: Ukuba awuqinisekanga malunga nendlela yokufaka i-azelaic acid kwindlela yakho yesiqhelo, dibana ne-dermatologist ngeengcebiso zomntu.
Ixesha lokuposa: Sep-21-2024
