● YintoniCapsaicin?
I-Capsaicin yikhompawundi eyenzeka ngokwemvelo efumaneka kwipepile yetshilisi ebanika ubushushu obubonakalayo. Ibonelela ngeenzuzo ezininzi, kubandakanya ukuthomalalisa iintlungu, ukulawulwa kwe-metabolic kunye nobunzima, impilo yentliziyo, kunye ne-antioxidant kunye ne-anti-inflammatory properties. I-Capsaicin isetyenziswa ngokubanzi kwizicelo zokupheka, kwiimveliso zonyango, kwizinto zokuthambisa, kunye nokulawula izinambuzane.
● IiPropati zoMzi neMichiza yeCapsaicin
1. Ukubunjwa kwemichiza
Igama leMchiza:I-8-Methyl-N-vanillyl-6-nonenamide
Ifomula yemolekyuli:C18H27NO3
Ubunzima beMolekyuli:305.42 g/mol
Ulwakhiwo:I-Capsaicin i-alkaloid enesakhiwo esiyinkimbinkimbi esibandakanya iqela le-vanillyl (uhlobo lwe-phenol) kunye nomsila omde we-hydrocarbon.
2. IiPropati zoMzimba
Imbonakalo:I-Capsaicin ngokuqhelekileyo ayinambala, i-crystalline ukuya kwi-waxy solid.
Umbala:Ayinambala ukuya kumthubi.
Ivumba:ICapsaicin inevumba elinukayo.
Ngcamla:Inoxanduva lobushushu, imvakalelo evuthayo xa idliwe.
Ukunyibilika kwamanzi:Inyibilika kancinci emanzini (malunga ne-28 mg / L kwi-25 ° C).
Ukunyibilika kwezinye izinyibilikisi:Inyibilika etywaleni, ether, acetone, kunye namafutha. Le nkcazo ye-solubility yenza ukuba ilungele ukusetyenziswa kwiifom ezahlukeneyo, kubandakanywa ama-creams e-topical kunye ne-extracts culinary.
Indawo yokunyibilika:ICapsaicin inendawo yokunyibilika emalunga ne-62-65°C (144-149°F).
Indawo yokuBilisa:I-Capsaicin ibola ngaphambi kokubilisa, ngoko ke ayinayo indawo yokubilisa echazwe kakuhle.
Ubuninzi:Ubuninzi be-capsaicin bumalunga ne-1.1 g/cm³.
3. Iipropati zeMichiza
Uzinzo:I-Capsaicin izinzile phantsi kweemeko eziqhelekileyo kodwa inokuhla xa ibonakaliswe ekukhanyeni, kubushushu, kunye nomoya ixesha elide.
Ukubola:Ibola kwiqondo lokushisa eliphezulu, yingakho ingenayo indawo yokubilisa echazwe kakuhle.
pH:I-Capsaicin ngokwayo ayinayo i-pH, kodwa inokunyibilika kwizisombululo ezinamaqondo ahlukeneyo e-pH. Ngokuqhelekileyo izinzile kwiindawo ezineasidi kunye nesiseko.
Iqela lePhenolic:Iqela le-vanilyl liqulethe iqela le-phenolic hydroxyl, elinegalelo ekusebenzeni kwakhona kunye nokunyibilika kwii-alcohols.
Iqela le-Amide:Unxibelelwano lwe-amide kwi-capsaicin lubalulekile kumsebenzi wayo webhayoloji, ngakumbi ukusebenzisana kwayo ne-TRPV1 receptor, enoxanduva lokuva ubushushu kunye neentlungu.
4. Umsebenzi webhayoloji
Ukusebenzisana ne-TRPV1 Receptor
I-Mechanism of Action: I-Capsaicin ibophelela kwi-receptor yesikhashana enokubakho i-vanilloid 1 (TRPV1) i-receptor, iprotheni efunyenwe kwi-sensory nerve endings. Oku kusebenzisana kubangela ukuvakalelwa kobushushu kunye neentlungu, yingakho i-capsaicin isetyenziselwa kwiimveliso zokunceda iintlungu.
Iipropati zeThermogenic
Iimpembelelo zeMetabolic: I-Capsaicin inokunyusa i-thermogenesis (ukuveliswa kobushushu) kunye nenkcitho yamandla, yingakho isoloko iqukwa kwizongezo zokulawula ubunzima.
● Imithombo yeCapsaicin
I-Capsaicin yikhompawundi eyenzeka ngokwemvelo efumaneka kwipelepele yetshili, eyinxalenye yohlobo lweCapsicum.
Iindidi eziqhelekileyo
I-Capsicum annuum: Olu hlobo lubandakanya uluhlu olubanzi lweepepile, ukusuka kwi-mild ukuya kushushu, njenge-bell pepper, i-jalapeños, kunye ne-cayenne pepper.
I-Capsicum frutescens: Ibandakanya iipepile ezifana ne-tabasco kunye ne-Thai chili pepper, ezaziwa ngobushushu bazo obuninzi.
I-Capsicum chinense: Yaziwa ngezinye zeepepile ezishushu ehlabathini, kuquka i-habaneros, iibhonethi ze-Scotch, kunye ne-ghost pepper edume kakubi (Bhut Jolokia).
I-Capsicum baccatum: Ibandakanya iindidi ezifana ne-Aji pepper, ezithandwayo kwisidlo saseMzantsi Melika.
I-Capsicum pubescens: Eyaziwa ngokuba yi-rocoto pepper, enencasa eyahlukileyo kunye neqondo lokushisa.
Umxholo weCapsaicinoid
I-Capsaicin kunye ne-Dihydrocapsaicin: Le yi-capsaicinoids eninzi kakhulu kwi-pepper, igalelo malunga ne-80-90% yomxholo we-capsaicinoid.
Ezinye i-Capsaicinoids: Iquka i-nordihydrocapsaicin, i-homocapsaicin, kunye ne-homodihydrocapsaicin, ekwafaka isandla ekushiseni kodwa ngamanani amancinci.
● Ziziphi iingeneloCapsaicin?
1. Ukuphelisa iintlungu
I-Topical Analgesic
I-1.Mechanism: I-Capsaicin isebenza ngokunciphisa i-P, i-neuropeptide ebandakanyekayo ekudluliseleni iimpawu zentlungu kwingqondo. Oku kwenza ukuba kusebenze ekunciphiseni ukuvakalelwa kweentlungu.
2.Izicelo: Isetyenziswa kwiikhrim, iigels, kunye neepatches ukukhulula intlungu kwiimeko ezifana ne-arthritis, i-muscle strains, kunye ne-neuropathy.
I-3.Ulawulo lweentlungu ezingapheliyo: Ukuphumelela ekulawuleni iimeko ezibuhlungu ezingapheliyo, kuquka i-post-herpetic neuralgia kunye ne-diabetic neuropathy.
2. Ulawulo lweMetabolic kunye nobunzima
Thermogenesis
I-1.Inkcitho yamandla eyongeziweyo: I-Capsaicin inokunyusa i-thermogenesis (ukuveliswa kobushushu) kunye nenkcitho yamandla, enokunceda ekulawuleni ubunzima.
I-2.Fat Oxidation: Ezinye izifundo zibonisa ukuba i-capsaicin inokunyusa i-oxidation ye-fat, inceda umzimba ukuba utshise amanqatha ngokufanelekileyo.
Ukunciphisa Umdla
Ukunciphisa I-Calorie Intake: I-Capsaicin ibonakaliswe ukunciphisa ukutya kunye nokutya kwekhalori, enokuba luncedo ekulahlekeni kwesisindo kunye nokulawula ubunzima.
3. Impilo yentliziyo
Ukulawulwa koxinzelelo lwegazi
I-1.Vasodilation: I-Capsaicin ikhuthaza i-vasodilation (ukwandiswa kwemithambo yegazi), enokunceda ukunciphisa uxinzelelo lwegazi.
I-2.I-Circulation ephuculweyo: Ukuhamba kwegazi okuphuculweyo kunokufaka isandla kwimpilo ye-cardiovascular health.
Amanqanaba eCholesterol
Ukuphuculwa kweProfayili yeLipid: Olunye uphando lubonisa ukuba i-capsaicin inokunceda ukuphucula iiprofayili ze-lipid ngokunciphisa i-cholesterol ye-LDL (embi) kunye nokwandisa i-cholesterol ye-HDL (elungileyo).
4. Impilo yokugaya ukutya
IiNzuzo zeGastrointestinal
I-1.Ivuselela Ukugaya: I-Capsaicin inokuvuselela i-digestive tract, ikhuthaza ukugaya okungcono kunye nokufunxa izondlo.
Iimpawu ze-2.Anti-Ulcer: Ngokuchasene neenkolelo eziqhelekileyo, i-capsaicin ingaba nemiphumo yokukhusela kwizilonda zesisu ngokukhuthaza ukukhuselwa kwe-mucus ekhuselayo.
5. Iipropati ze-Antioxidant kunye ne-Anti-Inflammatory
UkuNcitshiswa koxinzelelo lwe-Oxidative
I-Radical Scavenging yamahhala: I-Capsaicin inezakhiwo ze-antioxidant ezinceda ukukhusela iiseli kuxinzelelo lwe-oxidative kunye nomonakalo omkhulu wamahhala, ukunciphisa umngcipheko wezifo ezingapheliyo.
UkuNcitshiswa koKudumba
Iimpembelelo ezichasayo: I-Capsaicin ibonisa iziphumo ezichasayo, ezinokuthi zizuze iimeko ezibonakaliswe ngokuvuvukala okungapheliyo, njenge-arthritis kunye nesifo sofuba.
6. UThintelo loMhlaza
Anti-Cancer Properties
I-1.Apoptosis Induction: Ezinye izifundo zibonisa ukuba i-capsaicin inokubangela i-apoptosis (i-programmed cell death) kwiiseli zomhlaza, ezinokuthi zithintele ukukhula kwamathumba.
I-2.Iimpembelelo ezichasayo: I-Capsaicin inokuthintela ukwanda kweeseli zomhlaza, ukunciphisa umngcipheko wokunyuka komhlaza.
7. Impilo yokuphefumla
Ukuthomalalisa
I-1.Icoca iiNdawo zeNasal: I-Capsaicin inokusebenza njengento yokutshatyalaliswa kwendalo, inceda ukusula iimpumlo kunye nokunciphisa ukuxinana.
2. Izibonelelo zokuphefumla: Isenokunceda kwiimeko ezifana ne-rhinitis engapheliyo kunye ne-sinusitis ngokunciphisa ukuvutha kweempumlo kunye nokuveliswa kwe-mucus.
8. Impilo yolusu
Usetyenziso lwezihloko
I-1.Anti-Aging: Iimpawu ze-antioxidant ze-capsaicin zinokunceda ukukhusela ulusu kwixinzelelo lwe-oxidative, ezinokunciphisa iimpawu zokuguga.
2.Iimeko zesikhumba: I-Capsaicin creams ngamanye amaxesha isetyenziselwa ukunyanga iimeko zesikhumba ezifana ne-psoriasis ngokunciphisa ukudumba kunye neentlungu.
● Zithini izicelo zeCapsaicin?
1. Ukusetyenziswa kweCulinary
◇Iziqholo kunye Nencasa
Ubushushu kunye neNcasa:I-Capsaicin inoxanduva lobushushu kwi-pepper ye-chili, iyenza isithako esithandwayo kwiindawo ezininzi zokutya emhlabeni jikelele, kuquka i-Mexican, i-Indian, i-Thai kunye ne-Korean.
Iisosi ezishushu kunye ne-Seasonings: Sisithako esiphambili kwiisosi ezishushu, i-chili powders, kunye ne-spice blends, ukongeza i-spicy kick ezityeni.
◇Ukugcinwa Kokutya
Iinkcazelo ngeempawu zeAntimicrobial:I-Capsaicin ineempawu ze-antimicrobial ezinokunceda ukugcina ukutya ngokuthintela ukukhula kwebhaktheriya kunye ne-fungi.
2. Ukusetyenziswa kwamayeza
◇Ukuphelisa iintlungu
I-Topical Analgesics:I-Capsaicin isetyenziswa kwiikhrimu, iigels, kunye neepatches ukukhulula iintlungu ezivela kwiimeko ezifana ne-arthritis, i-muscle strains, kunye ne-neuropathy. Isebenza ngokunciphisa i-P, i-neuropeptide ebandakanyekayo ekudluliseni iimpawu zentlungu.
Ulawulo lweentlungu ezingapheliyo: Ukuphumelela ekulawuleni iimeko ezibuhlungu ezingapheliyo, kuquka i-post-herpetic neuralgia kunye ne-diabetic neuropathy.
◇Ulawulo lobunzima
Izongezo zokutya:I-Capsaicin ifakwe kwizongezo zokulawula ubunzima kwiipropati zayo ze-thermogenic, ezinokunyusa inkcitho yamandla kunye ne-fat oxidation.
Ukunciphisa Umdla:Ezinye izongezo zisebenzisa i-capsaicin ukunceda ukunciphisa ukutya kunye nokutya kwekhalori.
◇Impilo yentliziyo
Ummiselo woxinzelelo lwegazi:Izongezo zeCapsaicin zinokunceda ukunciphisa uxinzelelo lwegazi ngokukhuthaza i-vasodilation (ukwandiswa kwemithambo yegazi).
Ulawulo lweCholesterol:Olunye uphando lubonisa ukuba i-capsaicin inokuphucula iiprofayili ze-lipid ngokunciphisa i-cholesterol ye-LDL (embi) kunye nokwandisa i-cholesterol ye-HDL (elungileyo).
3. IiMveliso zokuCosmetic kunye nezoBuqu
◇Ukunyamekelwa koLusu
Iimveliso ezichasene nokuguga:Iimpawu ze-antioxidant zecapsaicininokunceda ukukhusela ulusu kuxinzelelo lwe-oxidative, olunokunciphisa iimpawu zokuguga.
Unyango lwangaphakathi:I-Capsaicin isetyenziswa kwiikhrimu kunye nezithambiso ukunyanga iimeko zolusu ezifana ne-psoriasis ngokunciphisa ukudumba kunye neentlungu.
◇Iimveliso eziNcincisayo kunye neAnti-Cellulite
Isiphumo seThermogenic:I-Capsaicin ifakwe kwezinye iimveliso zokuthambisa ezijolise ekunciphiseni ukubonakala kwe-cellulite kunye nokukhuthaza iziphumo zokunciphisa umzimba ngokusebenzisa iimpawu zayo ze-thermogenic.
4. Usetyenziso lwezoShishino nezoLimo
◇ Ulawulo Lwezinambuzane
Izitshabalalisi zendalo:I-Capsaicin isetyenziselwa ukwakhiwa kwe-pesticide yendalo ukuthintela izinambuzane ngaphandle kweekhemikhali eziyingozi. Isebenza ngokuchasene neentlobo ezahlukeneyo zezinambuzane kunye nezilwanyana.
Izigxothi zezilwanyana:Isetyenziswa kwiimveliso ezenzelwe ukugxotha izilwanyana ezinje ngenyamakazi, oonomatse, kunye neempuku ezigadini nakwizityalo.
◇Izixhobo Ezingabulali
Pepper Spray:I-Capsaicin sisithako esisebenzayo kwi-spray ye-pepper, isixhobo esingabulali sokuzikhusela esisetyenziswe ngokunyanzeliswa komthetho kunye nabahlali ukukhubaza abahlaseli ngokubangela ukucaphuka okukhulu kunye neentlungu.
5. UPhando noPhuhliso
◇UPhando lwaMayeza
Uphuhliso lweziyobisi:ICapsaicin ifundelwa iziphumo zayo zonyango ezinokubakho kwiimeko ezahlukeneyo zonyango, kubandakanya umhlaza, ukutyeba, kunye nezifo zentliziyo.
Iimvavanyo zeklinikhi: Uphando oluqhubekayo lujolise ekuqondeni ngcono iindlela ze-capsaicin kunye nokusetyenziswa kwayo kwiyeza.
◇Izifundo zeZondlo
IiNzuzo zempilo:Uphando luyaqhubeka nokuhlola izibonelelo zezempilo ze-capsaicin, kubandakanywa nemiphumo yayo kwi-metabolism, ulawulo lweentlungu, kunye nempilo ye-cardiovascular health.
Imibuzo eNxulumeneyo onokuthi ubenomdla kuyo:
● Ziziphi iziphumo ebezingalindelekangaCapsaicin?
Ngelixa i-capsaicin ibonelela ngeenzuzo ezininzi zempilo kwaye inoluhlu olubanzi lwezicelo, inokubangela iziphumo ebezingalindelekanga kwabanye abantu. Nalu uphononongo oluneenkcukacha lweziphumo ebezingalindelekanga kunye noqwalaselo lokhuseleko olunxulumene ne-capsaicin:
1. Imiba yeGastrointestinal
Ubuhlungu besisu: Ukutya inani elikhulu le-capsaicin kunokubangela intlungu yesisu kunye nokukhathazeka.
I-nausea kunye nokugabha: Amanani aphezulu e-capsaicin angakhokelela kwisicaphucaphu kunye nokuhlanza.
Urhudo: Abanye abantu banokufumana urhudo emva kokutya ukutya okuneziqholo okune-capsaicin.
2. Ulusu kunye ne-Mucous Membrane Irritation
Usetyenziso lwesihloko
Ukuvutha kokuvutha: I-Capsaicin creams kunye ne-ointments inokubangela ukuvutha kwesikhumba, ngakumbi xa isetyenziswe okokuqala.
Ububomvu kunye nokuDumba: Abanye abantu banokufumana ububomvu, ukudumba, kunye nokucaphuka kwindawo yesicelo.
Iintshukumo Zokwalana Nezinto: Nangona kunqabile, abanye abantu banokuba neziphumo eziguquguqukayo kwi-capsaicin, okukhokelela ekurhawuzeleleni, kwirhashalala, okanye kwi-hives.
Ukuqhagamshelana namehlo kunye neeMembranes ze-Mucous
Ukucaphuka kakhulu: I-Capsaicin inokubangela ukucaphuka okukhulu kunye nokuvutha komlilo xa idibana namehlo, impumlo okanye umlomo. Kubalulekile ukuhlamba izandla kakuhle emva kokuphatha iimveliso ze-capsaicin kwaye ugweme ukubamba ubuso.
3. Imiba yokuphefumla
Ukuphefumla
Ukukhohlela kunye nokuthimla: Ukuphefumla i-capsaicin powder okanye umphunga kunokubangela ukukhohlela, ukuthimla, kunye nokucaphuka komqala.
Ubunzima bokuphefumla: Kwiimeko ezinzima, ukuphefumla i-capsaicin kunokukhokelela kubunzima bokuphefumla kunye ne-bronchospasm, ngakumbi kubantu abane-asthma okanye ezinye iimeko zokuphefumla.
4. Iimpendulo ze-hypersensitivity
I-Anaphylaxis: Nangona inqabile kakhulu, ukusabela okunamandla okubangelwa yi-anaphylaxis kunokwenzeka, okubonakaliswa ubunzima bokuphefumla, ukuvuvukala kobuso kunye nomqala, kunye nokuhla ngokukhawuleza kwengcinezelo yegazi. Unyango olukhawulezileyo luyafuneka kwiimeko ezinjalo.
5. Ukusebenzisana okunokwenzeka kunye naMayeza
Amayeza oxinzelelo lwegazi
Iimpembelelo eziphuculweyo: I-Capsaicin inokunyusa imiphumo yeyeza zonyango lwegazi, ezinokukhokelela kwi-hypotension (uxinzelelo lwegazi oluphantsi). Kubalulekile ukujonga uxinzelelo lwegazi ngokusondeleyo kwaye udibane nomboneleli wezempilo malunga nohlengahlengiso olufanelekileyo lwedosi.
Anticoagulants kunye neziyobisi Antiplatelet
Ukunyuka koMngcipheko wokopha: I-Capsaicin inokunyusa ingozi yokopha xa ithathwa kunye ne-anticoagulants okanye i-antiplatelet drug. Ukubonisana nomboneleli wezempilo kucetyiswa ngaphambi kokusebenzisa izongezo ze-capsaicin.
6. Ukukhulelwa nokuncancisa
Iinkxalabo zoKhuseleko: Kukho uphando olulinganiselweyo malunga nokhuseleko lwe-capsaicin ngexesha lokukhulelwa kunye nokuncancisa. Kungcono ukudibana nomboneleli wezempilo ngaphambi kokusebenzisa iimveliso ze-capsaicin ukuba ukhulelwe okanye uncancisa.
7. ImiGaqo yoLungelo ngokubanzi
Thetha nababoneleli ngezempilo
Iimeko zonyango: Abantu abaneemeko zonyango eziphantsi, ezifana nokuphazamiseka kwesisu, iimeko zokuphefumla, okanye ukuvakalelwa kwesikhumba, kufuneka badibane nomboneleli wezempilo ngaphambi kokusebenzisa iimveliso ze-capsaicin.
Qala nge-Dose ephantsi: Ukunciphisa umngcipheko wemiphumo emibi, kuyacetyiswa ukuba uqale ngedosi ephantsi kwaye unyuse ngokuthe ngcembe njengoko umzimba wakho ulungisa.
Uvavanyo lwePatch
Uvavanyo lwe-allergies: Ukuba uqhelene ne-allergies, cinga ukwenza uvavanyo lwe-patch ngaphambi kokuba usebenzise iimveliso ze-capsaicin ze-topical ngokubanzi ukuqinisekisa ukuba awunampendulo ingalunganga.
● Ngubani ongafanele athabathecapsaicin?
Ngelixa i-capsaicin ibonelela ngeenzuzo ezininzi zempilo, ayifanelanga wonke umntu. Abantu abane-allergies okanye ukuva ubunzima kwi-capsaicin okanye i-pepper ebomvu kufuneka bayiphephe. Abantu abaneengxaki zesisu ezifana ne-IBS, GERD, okanye izilonda ze-peptic banokufumana iimpawu ezinzulu. Abo baneemeko zokuphefumla ezifana ne-asthma kufuneka bakuphephe ukuphefumla i-capsaicin. Abantu abanolusu olubuthathaka okanye amanxeba avulekileyo akufanele basebenzise iimveliso ze-capsaicin. Abasetyhini abakhulelweyo nabancancisayo, abantwana, kunye nabantu abathatha amayeza athile okanye abaneemeko ezithile zonyango kufuneka badibane nomboneleli wezempilo ngaphambi kokuba basebenzise i-capsaicin. Ukuqaphela ezi ngqwalasela kunokunceda ukuqinisekisa ukusetyenziswa okukhuselekileyo nokusebenzayo kwe-capsaicin.
● Ziziphi izifo ezinyangwa yi-capsaicin?
I-Capsaicin isetyenziselwa ukunyanga izifo ezahlukeneyo kunye neemeko, ngokuyinhloko ngenxa yokunciphisa intlungu, i-anti-inflammatory, kunye nemiphumo ye-metabolic. Isebenza kakuhle ekulawuleni iimeko ezibuhlungu ezingapheliyo ezifana ne-arthritis, intlungu ye-neuropathic, kunye ne-fibromyalgia. I-Capsaicin ikwasetyenziselwa ukukhulula iintlungu ze-musculoskeletal ezivela kwi-musculoskeletal strains, i-sprains, i-tendinitis, kunye ne-bursitis. Kwidermatology, inceda ukulawula iimeko zolusu ezifana ne-psoriasis kunye nokurhawuzelelwa okungapheliyo. Izongezelelo zeCapsaicin zinokunceda ekulawuleni ubunzima kunye nempilo ye-cardiovascular ngokwandisa i-thermogenesis, ukunciphisa ukutya, kunye nokuphucula iiprofayili ze-lipid. Ikwaxhasa impilo yokwetyisa kwaye inokuba neziphumo ezikhuselayo kwizilonda zesisu. Kwimpilo yokuphefumula, i-capsaicin isebenza njenge-decongestant yendalo kwaye iyanciphisa ukuvutha kweempumlo. Uphando olusakhulayo lucebisa iipropati ezinokuthi zichase umhlaza, nangona uphando oluninzi luyafuneka. Ukufaka i-capsaicin kwiirejimeni zonyango kunokubonelela ngeenzuzo ezahlukeneyo zempilo kunye nokuphucula umgangatho wobomi kubantu abanezi meko.
Ixesha lokuposa: Sep-25-2024
