Kuphando olwenziwayo, izazinzulu ziye zafumanisa ukubaD-ribose, imolekyuli yeswekile nje eqhelekileyo, inendima ebalulekileyo ekuveliseni amandla kwiiseli. Oku kufunyanisiweyo kuneempembelelo ezibalulekileyo ekuqondeni i-metabolism yeselula kwaye kunokukhokelela kunyango olutsha kuluhlu lwezifo, kubandakanya iimeko zentliziyo kunye nokuphazamiseka kwemisipha.
Inzululwazi ngasemvaD-Ribose: Ukutyhila iNyaniso:
D-riboseyinxalenye ephambili yeadenosine triphosphate (ATP), imolekyuli esebenza njengeyona mali iphambili yamandla kwiiseli. Abaphandi kudala besazi ukuba i-ATP ibalulekile ekunikezeni amandla iinkqubo zeselula, kodwa indima ethileD-ribosekwimveliso ye-ATP ihleli inqabile kude kube ngoku. Ukufunyaniswa kunika ukukhanya kwiindlela ezintsonkothileyo ze-biochemical ezixhasa imveliso yamandla eselula.
Iziphumo zolu phando zibanzi. Ngokuqonda indima yeD-ribosekwimveliso ye-ATP, izazinzulu zinokukwazi ukuphuhlisa iindlela zonyango ezijoliswe kuzo kwiimeko ezibonakaliswe ngokuphazamiseka kwemetabolism yamandla. Oku kunokuba nefuthe elinzulu kwizigulana ezinesifo senhliziyo, i-muscular dystrophy, kunye nezinye iziphazamiso ezibandakanya ukuveliswa kwamandla eselula.
Ngaphezu koko, ukufunyanwa kweD-riboseIndima 'kwimveliso yamandla eselula ivula iindlela ezintsha zophando kwiziphazamiso zemetabolism. Ngokufumana ukuqonda okunzulu malunga nendlelaD-riboseinegalelo kwi-ATP synthesis, izazinzulu ziyakwazi ukuchonga iithagethi zenoveli zophuhliso lwamachiza, ezinokukhokelela kunyango olusebenzayo kuluhlu lweemeko zemetabolism.
Ngokubanzi, ukufunyanwa kweD-riboseIndima yeseli kwimveliso yamandla eselula imele ukuqhubela phambili okukhulu ekuqondeni kwethu imetabolism yeselula. Oku kufunyanisiweyo kunamandla okuguqula unyango lwezifo ezinxulumene nokuveliswa kwamandla kwaye kunokuvula indlela yokuphuhliswa konyango olutsha olujolise kwiinkqubo ezisisiseko ze-metabolic. Njengoko izazinzulu ziqhubeka nokutyhila ubunzima bemveliso yamandla eselula, ukubakho kweempumelelo ezintsha kunyango lwezonyango kukhula kuthembisa ngakumbi.
Ixesha lokuposa: Aug-08-2024
