Yintoni iGinsenosides?
I-Ginsenosides zizithako ezibalulekileyo ezisebenzayo zeginseng. Zivela kwi-triterpenoid glycoside compounds kwaye ziyakwazi ukwahlula zibe yi-protopanaxadiol saponins (i-PPD-type saponins), i-protopanaxatriol saponins (i-PPT-type saponins) kunye nohlobo lwe-oleanane. Ngaphezulu kwe-40 ginsenosides ziye zahlukaniswa kwiingcambu ze-ginseng.
I-Ginsenosides ineempembelelo ezininzi zonyango ezifana ne-antioxidant, i-anti-inflammatory, i-vasodilation, i-anti-allergic, kunye ne-anti-diabetic. Ezinye ii-ginsenosides zibonisa iipropathi zazo zokuchasana nomhlaza ngokunciphisa umonakalo we-DNA, ukunciphisa ukubakho komkhosi kutshintsho, ukonyusa iliso lomzimba kunye ne-apoptosis yeseli. Ukongeza, i-ginsenosides inokuphucula ngokufanelekileyo ukusebenza kwamachiza e-chemotherapy yendabuko kunye nokuthintela umonakalo kwizicubu eziqhelekileyo.
Umxholo weGinsenosides iyonke kwiiNdawo ezahlukeneyo zeGinseng
| Inxalenye | Iyonke imixholo yeGinsenosides |
| Iingcambu ezisecaleni | 60.5% |
| Amagqabi | 15% |
| Amagqabi eGinseng | 7.6%-12.6% |
| Iingcambu zeGinseng fibrous | 8.5%-11.5% |
| Ulusu lweGinseng | 8.0%-8.8% |
| Ingcambu ye-ginseng | 2%-7% |
| Iingcambu ezincinci zeGinseng | 3% |
| Imbewu | 0.7% |
Iintlobo kunye neePropati zeMichiza yeGinsenosides
I-Ginsenosides zonke zinezakhiwo ezisisiseko ezifanayo, zonke ziqulethe i-sterane steroid nucleus ene-athomu ye-carbon engama-30 ehlelwe ngamakhonkco amane. Bahlulwe ngamaqela amabini ngokweendlela ezahlukeneyo ze-glycoside: uhlobo lwe-dammarane kunye nohlobo lwe-oleanane.
Uhlobo lweDammarine lubandakanya iindidi ezimbini:
I-Ginsenoside uhlobo-A, i-aglycone yi-20 (S) -protopanaxadiol. Iqulethe i-ginsenosides ezininzi, ezifana ne-ginsenoside Rg3, Rb1, Rb2, Rb3, Rc, Rd, Rh2 kunye ne-glycoside PD;
I-Ginsenoside uhlobo-B, i-aglycone yi-20 (S) -protopanaxadiol. Iqulethe i-ginsenoside Re, i-Rg1, i-Rg2, i-Rh1 kunye ne-glycoside PT.
Uhlobo lwe-Oleanane: uhlobo lwe-oleanolic acid-C, i-aglycone yi-oleanolic acid.
I-saponins iyonke ayikho i-hemolytic, uhlobo lwe-A luyi-anti-hemolytic, ngelixa uhlobo lwe-B kunye nohlobo lwe-C luyi-hemolytic.
| Iintlobo zeGinsenoside | Ukusebenza kakuhle |
| Rh2 | Unefuthe lokuthintela i-metastasis yeeseli zomhlaza kwamanye amalungu, ukwandisa ukhuseleko lomzimba, kunye nokubuyisela ngokukhawuleza ukuqina komzimba. Inefuthe elibalulekileyo lokuchasa imetastasis kwiiseli zomhlaza, kwaye inokuthatyathwa ngotyando ukomeleza ukuphiliswa kwenxeba kunye nokuchacha komzimba emva kotyando. I-bioavailability epheleleyo yi (16.1±11.3)%. |
| Rg | Inefuthe lokuvuselela inkqubo ye-nervous central, ukuxhathisa ukukhathala, ukuphucula imemori kunye nokukwazi ukufunda, kunye nokukhuthaza i-DNA kunye ne-RNA synthesis. Inefuthe lokuvuselela inkqubo ye-nervous central, ukuxhathisa ukukhathala, ukuphucula imemori kunye nokukwazi ukufunda, kunye nokukhuthaza i-DNA kunye ne-RNA synthesis. |
| Rg1 | Inokunciphisa ngokukhawuleza ukudinwa, ukuphucula ukufunda kunye nenkumbulo, kunye nokulibazisa ukuguga. Inomphumela wokuvuselela inkqubo ye-nervous central kunye nokuvimbela ukuhlanganiswa kweplatelet. |
| Rg2 | Inomphumela ochasayo, iphucula ngokukhawuleza ischemia ye-myocardial kunye ne-hypoxia, kwaye iphatha kwaye inqande isifo senhliziyo. |
| Rg3 | Inokuthi isebenze kwisigaba se-G2 somjikelezo wokuzala kweeseli, inqanda ukuhlanganiswa kweeprotheni kunye ne-ATP kwisigaba sangaphambili semitotic yamaseli omhlaza, ukunciphisa ukwanda kunye nokukhula kweeseli zomhlaza, kwaye kunemiphumo yokuthintela ukungena kweseli yomhlaza, ukumelana ne-tumor cell metastasis, ukukhuthaza i-apoptosis yeseli yethumba, kunye nokuthintela ukukhula kweseli yethumba. |
| Rg5 | Inhibit ukungena kweseli yomhlaza, i-anti-tumor cell metastasis, ikhuthaze i-tumor cell apoptosis, inqanda ukukhula kweeseli zethumba. |
| Rb1 | I-ginseng yaseMelika (i-ginseng yaseMelika) inomxholo ophezulu kwaye inamandla okuchaphazela amasende ezilwanyana kunye nokuphuhliswa kwe-embryonic yeegundane. Inomsebenzi wokuphucula inkqubo ye-choline, ukwandisa i-synthesis kunye nokukhululwa kwe-acetylcholine kunye nokuphucula imemori. |
| Rb2 | I-DNA kunye ne-RNA yokunyuswa kwe-synthesis, ukulawulwa kweziko lobuchopho kuneempembelelo zokuthintela inkqubo ye-nervous central, ukunciphisa i-calcium ye-intracellular, i-anti-oxidation, i-scavenging radicals yamahhala emzimbeni kunye nokuphucula ukulimala kwe-myocardial ischemia-reperfusion. |
| Rc | I-Ginsenoside-Rc yimolekyuli ye-steroid kwi-ginseng. Inomsebenzi wokuthintela iiseli zomhlaza. Inokwandisa umsebenzi wamadlozi. |
| Rb3 | Inokuphucula ukusebenza kwe-myocardial kwaye ikhusele amajoni omzimba omzimba. Ingasetyenziselwa ukunyanga ukusilela kwe-myocardial contractile okubangelwa zizizathu ezahlukeneyo. |
| Rh | Ineempembelelo zokuthintela inkqubo ye-nervous central, i-hypnotic, i-analgesic, ukuzola, i-antipyretic, kunye nokukhuthaza i-serum protein synthesis. |
| Rh1 | Ineempembelelo zokukhuthaza ukwanda kweeseli zesibindi kunye ne-DNA synthesis, kwaye ingasetyenziselwa ukunyanga nokukhusela i-hepatitis kunye ne-cirrhosis. |
| R0 | Ine-anti-inflammatory, detoxifying, and anti-thrombotic effects, inhibits acidic platelet aggregation, kwaye ineempembelelo ezichasayo ze-hepatitis kwaye isebenze i-macrophages. |
| Rh3 | Iziphumo ze-ginsenoside Rh3 ekwandeni kunye ne-apoptosis yeeseli zekholoni yomntu SW480. |
Anti-ithumba izithako
| Izithako | Ukusebenza kakuhle |
| Rh2 | I-Ginsenoside Rh2 monomer inempembelelo yokuthintela ukukhula kweeseli zomhlaza, inokubangela i-tumor cell apoptosis, ibuyisele umva umahluko ongaqhelekanga weeseli zethumba, kwaye imelane ne-tumor metastasis. Xa isetyenziswe ngokudibeneyo namachiza e-chemotherapy, inokuphucula ukusebenza kunye nokunciphisa ubuthi. Ukongeza kwimpembelelo ye-anti-tumor, i-ginsenosides ineempembelelo zokuphucula ukhuseleko lomzimba, i-antibacterial, ukuphucula i-cardiovascular and cerebrovascular blood supply insuffance, ukulawula inkqubo ye-nervous central, anti-fatigue, kunye nokulibazisa ukuguga. |
| Rh1 | Inokuthintela ukunamathela kunye nokungena kweeseli ze-tumor, ithintele ukwakheka kwemithambo yegazi emitsha yeeseli zomhlaza, ngaloo ndlela inqanda ukukhula kwethumba, ukusasazeka kunye ne-metastasis, kwaye inomsebenzi obalulekileyo wokuchasana nomhlaza. Inokuphucula kakhulu ukuhla kweeseli ezimhlophe zegazi ezibangelwa yi-radiotherapy, ichemotherapy kunye notyando, kwaye yenze i-rheology yegazi ithande ukuqheleka. Esi sithako sinefuthe elinamandla lokuthintela kunye ne-anti-cancer, linokuphucula ukusebenza komntu kunye nokusebenza komzimba, kwaye kunemiphumo ebalulekileyo ngokudibanisa notyando kunye ne-radiotherapy kunye ne-chemotherapy. |
| Rg5 | I-Rg5 inokwenza i-apoptosis yeeseli ezahlukeneyo zethumba. I-Rg5 ekhutshwe kwiginseng entle emnyama iqinisekisiwe kwiiseli zebele lomntu. I-Rg5 inokwenza i-apoptosis kunye nomonakalo we-DNA kwiiseli ezahlukeneyo zomhlaza womlomo wesibeleko. I-Aseries yovavanyo lwe-in vitro iqinisekisile ukuba i-ginsenoside Rg5 inefuthe elithintelayo kwiiseli zomhlaza we-esophageal. |
| Rh3 | I-Ginsenoside Rh3 inokuthintela ukwanda kweeseli zomhlaza wekholoni yomntu SW480 kwaye yenze i-apoptosis, kwaye umphumo uxhomekeke kwidosi kwaye uxhomekeke kwixesha. |
| i-APPD | I-20 (S) - I-Protopanaxadiol (i-aPPD) iyisithako esisebenzayo kunye nokusetyenziswa kweziyobisi eziveliswa yi-ginsenosides emva kwe-desugar metabolism kunye nokusebenza nge-flora yesisu, kwaye ine-spectrum ebanzi ye-anti-tumor effects. Kwiminyaka yakutshanje, iqela lophando likaWilliam Jia leYunivesithi yaseBritish Columbia lenze uthotho lwezifundo malunga nomsebenzi wokulwa nethumba le-APPD kwi-vivo kunye ne-in vitro, kwaye yafumanisa ukuba ineziphumo ezimbini ze-pharmacological. Kwelinye icala, inokubulala ngokuthe ngqo iiseli zethumba kwaye ikhuthaze i-apoptosis yazo; kwelinye icala, inokukhusela i-neurons kwizinto ze-cytotoxic. |
Yintoni Inzuzo YaGinsenosides?
Izibonelelo ze-ginsenosides, i-compounds esebenzayo efunyenwe kwi-ginseng, ibanzi kwaye ibe yinto yophando olubanzi. Ezinye iingenelo ezinokubakho ze-ginsenosides ziquka:
1. Umsebenzi wokuqonda: I-Ginsenosides ifundelwe amandla abo okuxhasa umsebenzi wokuqonda, kuquka inkumbulo, ukugxila, kunye nokucaca kwengqondo.
2. Amandla kunye ne-Vitality: I-Ginsenosides ikholelwa ukuba ineempawu ze-adaptogenic, ezinceda ukuxhasa amanqanaba ombane, ukunciphisa ukukhathala, nokukhuthaza amandla onke.
3. Inkxaso ye-Immune System: Olunye uphando lubonisa ukuba i-ginsenosides ineempembelelo ze-immune-modulating, ezinokuthi zixhase impendulo ye-immune enempilo.
4. Ulawulo loxinzelelo: I-Ginsenosides ithathwa njenge-adaptogens, oku kuthetha ukuba inceda umzimba ulungelelanise uxinzelelo kunye nokukhuthaza ukuvakalelwa kakuhle.
5. Impilo ye-Cardiovascular Health: Ezinye izifundo zihlolisise amandla e-ginsenosides ekuxhaseni impilo ye-cardiovascular health, kubandakanywa nemiphumo yabo kwixinzelelo lwegazi kunye nokujikeleza.
Kubalulekile ukuqaphela ukuba izibonelelo ezithile ze-ginsenosides ziyahluka ngokuxhomekeke kuhlobo lwe-ginseng kunye nokwakheka kwee-ginsenosides ezikhoyo. Njengaso nasiphi na isongezelelo okanye imveliso yendalo, kuyacetyiswa ukuba udibane nengcali yezempilo ukuze ufumane iingcebiso zomntu malunga nokusetyenziswa kwe-ginsenosides kwiinkxalabo zempilo ezithile.
Yintoni usetyenziso lweGinsenosides?
I-Ginsenosides inoluhlu olubanzi lwezicelo ezinokubakho ngenxa yeempawu zabo ezahlukeneyo ze-pharmacological. Ezinye zezicelo ze-ginsenosides ziquka:
1. Unyango Lwesintu: I-Ginsenosides isetyenziswe iinkulungwane kumayeza esintu, ngakumbi kwi-East Asia, ngenxa yeempawu zabo ze-adaptogenic kunye nokukhuthaza impilo.
2. Izongezelelo: I-Ginsenosides isetyenziswa ngokuqhelekileyo njengezithako ezisebenzayo kwizongezelelo zokutya kunye namalungiselelo emithi ejoliswe ekuxhaseni umsebenzi wokuqonda, amanqanaba amandla, kunye nokuphila kakuhle.
3. I-Pharmaceuticals: Uphando kwizicelo ezinokubakho zonyango lwe-ginsenosides lukhokelele ekusebenziseni kwabo kwiimveliso zamachiza, ngokukodwa ekuphuhliseni amachiza kwiimeko ezifana nokuncipha kwengqondo, ukukhathala, kunye noxinzelelo olunxulumene noxinzelelo.
4. Izithambiso: Ii-ginsenosides zikwasetyenziswa kwishishini lezinto zokuthambisa ngenxa yeenzuzo zabo ezinokubakhona eluswini, kubandakanywa iipropathi zokulwa nokuguga kunye ne-antioxidant.
5. Ukutya okuSebenzayo kunye neZiselo: I-Ginsenosides ifakwe kwizinto ezahlukeneyo zokutya ezisebenzayo kunye neziphuzo, ezifana neziphuzo zamandla kunye ne-tonics yezempilo, ukubonelela ngeenzuzo zempilo.
Yintoni I-Side Effect OfGinsenosides?
I-Ginsenosides ngokuqhelekileyo ithathwa njengekhuselekile xa isetyenziswe kwiidosi ezifanelekileyo, kodwa njengayo nayiphi na ikhompawundi ye-bioactive, inokuba nemiphumo enokubakho, ngakumbi xa isetyenziswe ngezixa eziphezulu. Ezinye iziphumo ezinokwenzeka ze-ginsenosides zinokubandakanya:
1. Ukungalali: Amanani aphezulu e-ginsenosides anokubangela ukuvuselela, okukhokelela kubunzima bokulala okanye ukuhlala ulele.
2. Imiba yokwetyisa: Abanye abantu basenokungaziva kakuhle ukucola ukutya, okufana nesicaphucaphu, urhudo, okanye isisu esibuhlungu, xa besebenzisa iidosi eziphezulu zeginsenosides.
3. Uxinzelelo lwegazi: Kwiimeko ezinqabileyo, ukusetyenziswa ngokugqithiseleyo kwe-ginsenosides kunokukhokelela ekunyuseni uxinzelelo lwegazi.
4. Iintshukumo Zokwalana Nezinto: Nangona kuqhelekile, abanye abantu basenokungadibani nee<em>ginsenosides, nto leyo ekhokelela kwiimpawu ezifana nerhashalala, ukurhawuzelelwa, okanye ukuphefumla nzima.
5. Iimpembelelo zeHormonal: I-Ginsenosides ingaba nemiphumo epholileyo ye-hormonal, kwaye kwezinye iimeko, inokusebenzisana neyeza ezinxulumene ne-hormone okanye iimeko.
Kubalulekile ukuba uqaphele ukuba iziphumo ze-ginsenosides zinokwahluka ngokuxhomekeke kumntu, uhlobo oluthile lwe-ginseng, kunye nedosi. Njengaso nasiphi na isongezelelo okanye imveliso yendalo, kuyacetyiswa ukuba udibane nengcali yezempilo phambi kokuba usebenzise i-ginsenosides, ngakumbi kwabo baneemeko zempilo eziphantsi okanye abo bathatha amayeza.
Imibuzo eNxulumeneyo onokuthi ubenomdla kuyo:
Ngubani ongafanele athathe iginseng?
Abantu abathile kufuneka balumke okanye bakuphephe ukuthatha i-ginseng, kubandakanya:
1. Abasetyhini abakhulelweyo okanye abancancisayo: Ukhuseleko lwe-ginseng ngexesha lokukhulelwa kunye nokuncancisa akuzange kufundwe ngokubanzi, ngoko kuyacetyiswa ngokubanzi ukuba uphephe ukusetyenziswa kwayo ngala maxesha.
2. Abantu abane-Autoimmune Disorders: I-Ginseng inokuvuselela amajoni omzimba, anokuthi aqhubele phambili iimeko ze-autoimmune. Kuyacetyiswa ukuba abantu abanengxaki ye-autoimmune badibane nengcali yezempilo ngaphambi kokusebenzisa iginseng.
3. Abantu abaneengxaki zokopha: I-Ginseng inokuba nemiphumo epholileyo ye-anticoagulant, ngoko ke abantu abaneengxaki zokopha okanye abo bathatha amayeza okunciphisa igazi kufuneka basebenzise i-ginseng ngokuqaphela kwaye phantsi kwesikhokelo somboneleli wezempilo.
4. Abantu abaneeMeko eziKhethekileyo zeHormone-Sensitive: Ngenxa yeziphumo zehomoni ezinokubakho zeginseng, abantu abaneemeko zehomoni-sensitive ezifana nomhlaza wamabele, uterine fibroids, okanye i-endometriosis kufuneka badibane nogqirha wezempilo phambi kokuba basebenzise iginseng.
5. Abo Banengxaki Yokungalali okanye Yokuxhalaba: I<em>ginseng isenokuba nemiphumo evuselelayo, ngoko abantu abanengxaki yokuphuthelwa okanye abanengxaki yokuxhalaba bafanele balumke xa besebenzisa iginseng, ingakumbi xa besebenzisa idosi eninzi.
Ngaba i-ginsenosides steroids?
I-ginsenosides ayizo-steroids. Ziliqela leekhompawundi zendalo ezifumaneka kwisityalo seginseng. Ngelixa i-ginsenosides inokuba neenzuzo ezahlukeneyo zempilo, zakhiwe kwaye zisebenza ngokwahlukileyo kwi-steroids. I-steroids ludidi lweehomoni kunye ne-lipids ezidlala indima ebalulekileyo kwimetabolism yomzimba, umsebenzi wokuzivikela komzimba, kunye nezinye iinkqubo zomzimba. Ngokwahlukileyo, i-ginsenosides i-saponins, uhlobo lwe-glycoside compound, kwaye zaziwa nge-adaptogenic kunye neempawu zokukhuthaza impilo.
Yeyiphi iginseng eyona iphezuluginsenosides?
Iintlobo zeginseng ezinowona mxholo uphezulu weginsenoside yiPanax ginseng, ekwabizwa ngokuba yiAsian okanye iginseng yaseKorea. Olu hlobo lwe-ginseng lwaziwa ngoxinzelelo olutyebileyo lwe-ginsenosides, ezizikhompawundi ze-bioactive ezinoxanduva loncedo lwezempilo lwesityalo. I-Panax ginseng ixabiseke kakhulu kumayeza esintu kwaye ihlala isetyenziselwa i-adaptogenic kunye neempawu zayo ezivuselelayo. Xa ufuna iimveliso ze-ginseng ezinomxholo ophezulu we-ginsenoside, iPanax ginseng lukhetho oludumileyo.
Ngaba kulungile ukuthatha i-ginseng yonke imihla?
Ngokuqhelekileyo kuthathwa njengekhuselekile kubantu abaninzi ukuba bathathe i-ginseng yonke imihla ixesha elifutshane. Nangona kunjalo, ukusetyenziswa kwexesha elide le-ginseng kunokukhokelela kwiziphumo ebezingalindelekanga okanye ukusebenzisana namayeza. Ke ngoko, kubalulekile ukusebenzisa i-ginseng phantsi kwesikhokelo sokhathalelo lwezempilo, ngakumbi ukuba uceba ukuyithatha yonke imihla ixesha elide. Ukubonisana nomboneleli wezempilo kunokunceda ukuqinisekisa ukuba i-ginseng ifanelekile kwiimfuno zakho zezempilo kwaye ayidibanisi nawaphi na amayeza okanye iimeko esele zikhona.
Ngaba i-ginseng yonyusa i-testosterone?
I-Ginseng iye yacetyiswa ukuba ibe nemiphumo enokubakho kumanqanaba e testosterone, nangona ubungqina bungagqibekanga. Olunye uphando lubonise ukuba i-ginseng inokuba nempembelelo encinci kumanqanaba e testosterone, ngokuxhasa iindlela ezibandakanyekayo kwimveliso ye testosterone. Nangona kunjalo, uphando oluninzi luyafuneka ukuze uqonde ngokupheleleyo ubungakanani bempembelelo yeginseng kwi testosterone.
I-ginseng yenza ntoni kwiihomoni zabasetyhini?
I-Ginseng inokuba nemiphumo enokubakho kwiihomoni zabasetyhini, nangona uphando kule ndawo lungagqibekanga ngokupheleleyo. Olunye uphando lucebise ukuba i-ginseng inokuba neepropathi ze-adapogenic ezinokunceda ukuxhasa ibhalansi yehomoni kwabasetyhini, ngakumbi ngexesha loxinzelelo okanye ukuguquguquka kwehomoni. Ukongeza, i-ginseng iye yaphononongwa ngezibonelelo zayo ezinokubakho ekujonganeni neempawu ezinxulumene nokuyeka ukuya exesheni, ezinjengokukhanya okutshisa kunye nokutshintsha kwemo.
Ixesha lokuposa: Sep-12-2024
