Yintoni iGlabridin?
I-Glabridin i-flavonoid ekhutshwe kwiingcambu ze-licorice (i-Glycyrrhiza glabra) kwaye inemisebenzi eyahlukeneyo yezinto eziphilayo kunye neenzuzo zempilo. I-glabridin iyaziwa ngokuba mhlophe okunamandla, i-antioxidant kunye ne-anti-inflammatory properties kwaye isetyenziswa ngokubanzi kukhathalelo lwesikhumba kunye nezithambiso.
I-Glycyrrhiza glabra L. yimifuno engapheliyo ekhula kumazantsi eYurophu, e-Asiya, kunye nommandla weMeditera. Ityalwa kakhulu eRashiya, eSpain, eIran naseIndiya. Isityalo se-G. glabra si malunga ne-1-1.5 yeemitha ubude, kunye namaqabunga amancinci amnyama, aphuzi, aluhlaza okwesibhakabhaka, kunye neentyantyambo ze-violet, kunye ne-rhizome emnandi.
IGlabridin yenye yeeflavonoids eziphambili kwiGlycyrrhiza glabra. Ibonisa i-anti-free radical oxidation effect kwi-cytochrome P450 / NADPH inkqubo ye-oxidation, kwaye inokuthintela kakhulu i-radicals yamahhala eveliswa ngexesha lenkqubo ye-metabolism emzimbeni ukukhusela i-oxidation-sensitive biomacromolecules (i-low-density lipoprotein LDL, DNA) kunye iindonga zeseli ekubeni zonakaliswe yi-radical oxidation yasimahla. Oku kunokuthintela kunye nokunyanga utshintsho oluthile lwe-pathological ezinxulumene ne-radical oxidation yamahhala, njenge-atherosclerosis kunye nokuguga kweeseli. Ukongeza, i-glabridin inefuthe elithile lokunciphisa i-lipids yegazi kunye noxinzelelo lwegazi. Uphando lwaseNtaliyane luye lwaqinisekisa ukuba i-Glabridin inefuthe lokunciphisa ukutya, elinokunciphisa amanqatha ngaphandle kokunciphisa ubunzima. Emva kovavanyo oluphindaphindiweyo, iziphumo eziphambili zilandelayo: 1. I-Whitening, inhibiting melanin; 2. Impembelelo yokuchasa; 3. Isiphumo se-Antioxidant; 4. I-Antibacterial.
IiPropati zoMzimba kunye nezeMichiza yeGlabridin
1. Ulwakhiwo lweMichiza
Igama leKhemikhali: Glabridin
Ifomula yeMichiza: C20H20O4
Ubunzima beMolekyuli: 324.37 g / mol
Iimpawu zeSakhiwo: I-Glabridin yimbumba ye-flavonoid ene-flavonoid backbone structure. Iquka amakhonkco amabini anevumba elimnandi (A kunye no-B) adityaniswe yibhulorho enekhabhoni emithathu eyenza umsesane ovaliweyo wepirani.
2. IiPropati zoMzimba
Imbonakalo: I-Glabridin ibonakala imhlophe okanye i-yellow crystalline powder.
Ukunyibilika:
Amanzi: Ayinyibiliki kakuhle emanzini.
Izinyibilikisi ze-Organic: Zinyibilika kwizinyibilikisi ze-organic ezifana ne-ethanol, i-methanol, kunye ne-propylene glycol.
Indawo yokunyibilika: Ngokumalunga ne-156-158 ° C (313-316 ° F).
Ivumba: I-Glabridin ngokuqhelekileyo ayinayo iphunga elicacileyo.
3. Iipropati zeMichiza
Ukuzinza: I-Glabridin izinzile phantsi kweemeko eziqhelekileyo kodwa iyakwazi ukuhla xa ibonakaliswe ekukhanyeni, ukushisa, okanye kwiimeko ze-acidic. Kucetyiswa ukuba uyigcine kwindawo epholileyo, eyomileyo, kude nelanga elithe ngqo.
Ubuzwe be-pH: I-Glabridin inovelwano kutshintsho lwe-pH kwaye inokunciphisa kwiindawo ezine-acidic kakhulu okanye ezisisiseko.
I-reactivity: Njenge-flavonoid, i-glabridin inokuthi isebenze kwiikhemikhali eziqhelekileyo ezinxulumene ne-phenolic compounds, ezifana ne-oxidation kunye nokudibanisa.
Ziziphi iiNzuzo zeGlabridin?
1. Ulusu lube mhlophe kunye nokuKhanya
- Ukuvinjelwa kweTyrosinase: I-Glabridin iyaziwa kakhulu ngeempawu zayo ezimhlophe zesikhumba. Ithintela umsebenzi we-tyrosinase, i-enzyme ebalulekileyo kwimveliso ye-melanin, ngaloo ndlela inciphisa ukwakheka kwamabala amnyama kunye ne-hyperpigmentation.
-Nokuba ithoni yolusu: Ngokunciphisa i-melanin synthesis, i-glabridin inceda ekufezekiseni ithoni yesikhumba kunye nebala eliqaqambileyo.
2. Iipropati ze-Antioxidant
- I-Free Radical Scavenging: I-Glabridin inezixhobo ezinamandla ze-antioxidant, ezinceda ekunciphiseni ii-radicals zamahhala. Oku kunciphisa uxinzelelo lwe-oxidative kwaye kuthintela umonakalo weselula.
- I-Anti-Aging: Umsebenzi we-antioxidant we-glabridin unceda ekunciphiseni iimpawu zokuguga, njengemigca emihle, imibimbi, kunye namabala obudala, ngokukhusela ulusu kumonakalo we-oxidative.
3. Iimpembelelo ezichasene nokudumba
- Ukunciphisa Ukuvuvukala: I-Glabridin ibonisa iimpawu ezichasayo, ezinceda ekunciphiseni ukuvuvukala kwesikhumba, ubomvu kunye nokuvuvukala.
-Impembelelo epholisayo: inokuthomalalisa ulusu olucaphukileyo kwaye iluncedo kwiimeko ezinje ngamaqhakuva, i-eczema kunye ne-rosacea.
4. Umsebenzi we-Antimicrobial
- Ukuvinjelwa kweePathogens: I-Glabridin ibonise iimpawu ze-antimicrobial ngokuchasene neebhaktheriya ezahlukeneyo kunye nefungi. Oku kwenza kube luncedo ekuthinteleni nasekunyangeni usulelo lolusu.
- Unyango lwe-Acne: I-antimicrobial kunye ne-anti-inflammatory properties yenza i-glabridin isebenze ekunyangeni i-acne ngokunciphisa ukukhula kwebhaktheriya kunye nokuvuvukala.
5. Ukhuseleko lwe-UV
- Ukhuseleko lwefoto: I-Glabridin inokubonelela ngezinga elithile lokukhusela kwimitha ye-UV. Inceda ekunciphiseni umonakalo wolusu olubangelwa yi-UV, njengokutshiswa lilanga kunye nokufota.
- Impembelelo ye-Synergistic: Xa isetyenziswe ngokudibanisa nezinye i-sunscreen agents, i-glabridin inokuphucula umphumo we-photoprotective jikelele.
6. UkuPhiliswa Kwenxeba
- Ukukhuthaza ukuPhilisa: I-Glabridin inokukhuthaza ukuphulukiswa kwesilonda ngokunciphisa ukuvuvukala kunye noxinzelelo lwe-oxidative, kunye nokuvuselela ukuvuselelwa kweeseli zesikhumba.
- Ukuncitshiswa kweScar: Isenokunceda ekunciphiseni ukubonakala kweziva ngokukhuthaza ukuvuselelwa kolusu olusempilweni.
7. Ukunyamekelwa kweNwele
- Impilo ye-scalp: I-Glabridin ye-anti-inflammatory kunye ne-antimicrobial properties inokuzuza impilo ye-scalp, ukunciphisa i-dandruff kunye ne-scalp irritation.
- Ukukhula kweenwele: Ngokuphucula impilo ye-scalp, i-glabridin inokukhuthaza ukukhula kweenwele ezinempilo.
Zithini Izicelo ZeGlabridin?
Izithambiso kunye ne-Skincare
1.Skin Whitening Products
- I-Whitening Creams kunye neSerums: I-Glabridin iyisithako esibalulekileyo kwiimveliso ezininzi ezimhlophe zesikhumba kunye nokukhanya ngenxa yokukwazi ukuvimbela umsebenzi we-tyrosinase kunye nokunciphisa ukuveliswa kwe-melanin.
- I-Spot Treatments: Isetyenziswe kwimixube ejoliswe ekunciphiseni amabala amnyama, i-hyperpigmentation, kunye nethoni yesikhumba esingalinganiyo.
2.Anti-Aging Products
- I-Anti-Aging Creams kunye ne-Lotions: Iimpawu ze-antioxidant ze-glabridin zinceda ekunciphiseni iimpawu zokuguga, njengemigca emihle, imibimbi kunye namabala obudala.
-Iikhrimu zamehlo: zihlala zibandakanyiwe kwiikhrimu zamehlo ukunciphisa izangqa ezimnyama kunye nokukhukhumala.
3.Anti-ukudumba kunye nemveliso Soothing
- IiGel kunye neeCreams ezipholileyo: I-Glabridin ye-anti-inflammatory properties yenza ukuba ifaneleke kwiimveliso ezenzelwe ukuthomalalisa ulusu olunomsindo okanye oluvuthayo.
- Unyango lwe-acne: Isetyenziselwa kwiimveliso zonyango lwe-acne ukunciphisa ukuvuvukala kunye nokukhula kwebhaktheriya.
4.Iimveliso zokuKhusela ilanga
- I-Sunscreens: I-Glabridin inokubandakanywa kwi-sunscreens ukubonelela ngokhuseleko olongezelelweyo kumonakalo wesikhumba owenziwe yi-UV.
- Ukhathalelo lwasemva kweLanga: Isetyenziswa kwiimveliso zasemva kwelanga ukuthomalalisa nokulungisa ulusu olutshiswe lilanga.
Amachiza
1. Amayeza asentloko
- I-Anti-Inflammatory Creams: Isetyenziselwa amayeza okunyanga ukunyanga izifo zesikhumba ezivuthayo ezifana ne-eczema, i-psoriasis, kunye ne-dermatitis.
- Amafutha okuPhilisa amanxeba: Ibandakanyiwe kwiifomyula ezijolise ekukhuthazeni ukuphulukiswa kwesilonda kunye nokunciphisa ukubunjwa kwamanxeba.
2. Izongezo zoMlomo
- I-Antioxidant Supplements: Iimpawu ze-antioxidant ze-Glabridin zenza ukuba ibe yinto ebalulekileyo kwizongezelelo zomlomo ezijoliswe ekunciphiseni uxinzelelo lwe-oxidative kunye nokukhuthaza impilo yonke.
- I-Immune Boosters: Isetyenziselwa izongezo ezenzelwe ukunyusa ukusebenza komzimba ngenxa yeempawu zayo ezichasayo kunye ne-antimicrobial.
Ukhathalelo lweNwele
1.Unyango lwe-scalp
- I-Anti-Dandruff Shampoos: I-Glabridin ye-antimicrobial kunye ne-anti-inflammatory properties yenza ukuba isebenze ekunyangeni i-dandruff kunye ne-scalp irritation.
- I-Scalp Serums: Isetyenziselwa kwiiserum ze-scalp ukukhuthaza indawo enempilo ye-scalp kwaye inokukhuthaza ukukhula kweenwele.
2.Ii-Hair Conditioners
- I-Conditioners kunye neeMaski zeNwele: Ibandakanyiwe kwiimveliso zokunakekelwa kweenwele ukubonelela ngokhuseleko lwe-antioxidant kunye nokuphucula impilo yeenwele.
Ukutya kunye neZiselo
Ukutya okuSebenzayo
- Iziselo zeMpilo: I-Glabridin inokongezwa kwiziphuzo zezempilo kunye neziyobisi ezisebenzayo ukubonelela ngeenzuzo ze-antioxidant kunye ne-anti-inflammatory.
- Iibhari zeZondlo: Zisetyenziswa kwiibhari zesondlo kunye nokutya okujoliswe ekukhuthazeni impilo yonke kunye nokuphila kakuhle.
Uphando nophuhliso
Uphando lweBiomedical
- Uphando lweCancer: I-Glabridin iphononongwa ngeempawu zayo ezichasene nomhlaza, kubandakanya ukukwazi ukuthintela ukukhula kweeseli zomhlaza kunye nokwenza i-apoptosis.
- UPhando lweSifo esingapheliyo: Kuphandwe ngeenzuzo ezinokuthi zikwazi ukulawula izifo ezingapheliyo ezifana nesifo sikashukela kunye nezifo zenhliziyo ngenxa yeempawu zayo ezichasayo kunye ne-antioxidant.
Imibuzo eNxulumeneyo onokuthi ubenomdla kuyo:
Kuthatha ixesha elingakanani ukufumana i-licorice extractiglabridinukukhanyisa ulusu?
Ixesha elithatha i-licorice extract equlethe i-glabridin yokukhanyisa ulusu lunokwahluka ngokuxhomekeke kwizinto ezininzi, kubandakanywa ukuxinwa kwe-glabridin kwimveliso, ubuninzi bokusetyenziswa, uhlobo lwesikhumba somntu, kunye nobukhulu be-hyperpigmentation. Nazi ezinye izikhokelo jikelele kunye neengqwalasela:
1. Ixesha elimiselweyo
- Iziphumo zokuqala: Abanye abasebenzisi banokuqala ukubona ukuphuculwa kokuqala kwithoni yesikhumba kunye nokunciphisa i-hyperpigmentation kwiiveki ezi-2 ukuya kwezi-4 zokusetyenziswa rhoqo.
- Iziphumo eziBalulekileyo: Iziphumo eziphawuleka ngakumbi nezibalulekileyo ezikhanyisa ulusu ngokuqhelekileyo zenzeka emva kweeveki ezisi-8 ukuya kwezili-12 zokusetyenziswa rhoqo.
2. Imiba enempembelelo kwimpumelelo
Ukugxilwa kweGlabridin
- Iingqwalasela eziPhakamileyo: Iimveliso ezinoxinzelelo oluphezulu lwe-glabridin (umzekelo, i-0.5% ukuya kwi-1%) inokuvelisa ngokukhawuleza kunye neziphumo ezicacileyo.
-Uxinzelelo olusezantsi: Iimveliso ezinoxinzelelo olusezantsi zinokuthatha ixesha elide ukubonisa iziphumo ezibonakalayo.
Ukuphindaphinda kosetyenziso
- Ukusetyenziswa kwemihla ngemihla: Ukusebenzisa imveliso kanye okanye kabini yonke imihla, njengoko kucetyiswa, kunokuphucula ukusebenza kunye nokukhawulezisa iziphumo.
- Ukusetyenziswa okungahambelaniyo: Ukusetyenziswa okungaqhelekanga kunokulibazisa iziphumo ezibonakalayo kunye nokunciphisa ukusebenza kakuhle.
Uhlobo lwesikhumba kunye neMeko
- Uhlobo lolusu: Abantu abaneetoni zolusu ezikhaphukhaphu banokubona iziphumo ngokukhawuleza xa kuthelekiswa nabanolusu olumnyama.
- Ubunzima be-Hyperpigmentation: I-hyperpigmentation encinci ingaphendula ngokukhawuleza kunyango, ngelixa iimeko ezinzima kakhulu zingathatha ixesha elide ukubonisa ukuphuculwa.
3. INkqubo yokuNcedisa iSkincare
-Ukukhuselwa kwelanga: Ukusebenzisa i-sunscreen yonke imihla kubalulekile xa usebenzisa iimveliso ezikhanyisa ulusu ukunqanda ngakumbi umbala kunye nokukhusela ulusu kumonakalo we-UV.
- Ukufuma: Ukugcina ulusu lufumile kakuhle kunokuphucula ukufunxa kunye nokusebenza kweemveliso ezine-glabridin.
- Ukukhutshwa: Ukukhutshwa rhoqo kunokunceda ukususa iiseli zesikhumba ezifileyo kunye nokukhuthaza ukungena kwezithako ezisebenzayo, ezinokukhawuleza iziphumo.
4. Izifundo zeklinikhi kunye nobungqina
- Izifundo zeklinikhi: Ezinye izifundo zeklinikhi zibonise ukuba i-glabridin inokunciphisa kakhulu i-hyperpigmentation kunye nokuphucula ithoni yesikhumba ngaphakathi kwe-8 kwiiveki ze-12 zokusetyenziswa rhoqo.
-Ubungqina bomsebenzisi: Abasebenzisi abaninzi baxela ukubona ukuphuculwa okubonakalayo kwithoni yesikhumba kunye nokuncipha kwamabala amnyama kwiiveki ezimbalwa ukuya kwiinyanga ezimbalwa zokusetyenziswa rhoqo.
Ziziphi iziphumo ebezingalindelekanga zeiglabridin?
I-Glabridin inemisebenzi eyahlukeneyo yezinto eziphilayo kunye neenzuzo zempilo, kodwa kwezinye iimeko, ukusebenzisa iimveliso eziqukethe i-glabridin kunokubangela imiphumo ethile. Ezi zilandelayo ziziphumo ebezingalindelekanga kunye nezilumkiso ze-glabridin:
1. Ukucaphuka kolusu kunye ne-Allergic Reactionns
Ukucaphuka kolusu
- Iimpawu: Isenokubandakanya ububomvu, ukudumba, ukurhawuzelelwa, ukurhawuzelelwa, okanye ukutshisa.
- Izizathu: Ukukhathazeka kwesikhumba kwi-glabridin okanye ezinye izithako kwimveliso kunokubangela ukucaphuka okuncinci kwesikhumba.
Iintshukumo zokwalana
- Iimpawu: Isenokuquka irhashalala, irhashalala, ukudumba, okanye ukurhawuzelelwa kakhulu.
- Izizathu: Ukwaliwa kwi-glabridin okanye ezinye izithako kwimveliso, ezinokuthi zibangele ukusabela komzimba.
2. Ukubonakala kwefoto
- Ukwandiswa kweSensitivity ekukhanyeni kwelanga: i-glabridin inokunyusa ukuvakalelwa kwesikhumba ekukhanyeni kwelanga, okukhokelela ekutshisweni kwelanga okanye i-photosensitivity dermatitis.
- Ukuthintela: Xa usebenzisa iimveliso eziqukethe i-glabridin, kucetyiswa ukuba usebenzise i-sunscreen ebanzi kwaye ugweme ukukhanya kwelanga ixesha elide.
3. Iziphumo zeHormonal
- Umsebenzi onokwenzeka weHormonal: Ngelixa i-glabridin ijoliswe ngokuyintloko ukusetyenziswa kwe-topical, amacandelo athile e-licorice (afana ne-glycyrrhizic acid) ayaziwa ngokuba nemiphumo efana ne-steroid enokuthi ichaphazele ibhalansi ye-hormone.
- Ukuqwalaselwa: Xa usebenzisa iimveliso eziqukethe i-glabridin ngobuninzi bexesha elide, kufuneka ubeke ingqalelo ukuba uqwalasele ukuba kukho iimpawu zokungalingani kwehomoni.
4. Ukusebenzisana nezinye izithako ze-Skincare
- Ukusebenzisana okunokwenzeka: i-glabridin inokusebenzisana nezinye izithako ezisebenzayo (ezifana ne-vitamin C, i-retinol, njl.), ezichaphazela ukusebenza kwayo okanye ukwandisa umngcipheko wemiphumo emibi.
- Isincomo: Xa usebenzisa iimveliso eziqukethe i-glabridin, kucetyiswa ukuba ugweme ukusetyenziswa okufanayo kwezinye izithako ezinamandla ezisebenzayo okanye ukubonisana nodermatologist ngaphambi kokusetyenziswa.
5. Iimpembelelo zeNkqubo
-Ukufunxa okulinganiselweyo:iglabridinisetyenziswa ikakhulu kusetyenziso lwangaphandle kwaye inenkqubo encinci yokufunxa, ngoko ke iziphumo ebezingalindelekanga zenkqubo azixhaphakanga.
- Isilumkiso: Ukuba ufumana nakuphi na ukungakhululeki okanye ukusabela okungaqhelekanga, kufuneka uyeke ukuyisebenzisa ngokukhawuleza kwaye udibane nogqirha wakho.
6. Ukukhulelwa nokuncancisa
- Iinkxalabo zoKhuseleko: Kukho idatha elinganiselweyo ngoku kukhuseleko lwe-glabridin kubasetyhini abakhulelweyo nabancancisayo.
- Isincomo: Abasetyhini abakhulelweyo nabahlengikazi kufuneka badibane nodokotela wabo ngaphambi kokusebenzisa iimveliso ezine-glabridin.
Ixesha lokuposa: Sep-21-2024
