Yintoni iSulforaphane?
I-Sulforaphane yi-isothiocyanate, efunyenwe nge-hydrolysis ye-glucosinolate nge-myrosinase enzyme kwizityalo. Ininzi kwizityalo ze-cruciferous ezifana ne-broccoli, i-kale, kunye ne-carrots ejikelezayo emantla. Yinto eqhelekileyo i-antioxidant kunye neyona nto isebenzayo yesityalo esisebenzayo kwimiphumo echasene nomhlaza efumaneka kwimifuno.
IiPropati zoMzi kunye nezeMichiza yeSulforaphane
Iimpawu ezibonakalayo
1. Imbonakalo:
-I-Sulforaphane ihlala ingenambala ukuya kumthubi yikristale eqinileyo okanye ulwelo olunamafutha.
2. Ukunyibilika:
-Ukunyibilika kwamanzi: I-Sulforaphane ine-solubility ephantsi emanzini.
-I-Solubility kwi-organic solvents: I-Sulforaphane ine-solubility efanelekileyo kwi-solvents yezinto eziphilayo ezifana ne-ethanol, i-methanol kunye ne-dichloromethane.
3. Indawo yokunyibilika:
- Indawo yokunyibilika ye-Sulforaphane isuka kwi-60-70 °C.
4. Indawo yokuBilisa:
- Indawo yokubilisa ye-Sulforaphane malunga ne-142 ° C (kuxinzelelo lwe-0.05 mmHg).
5. Ubuninzi:
- Ubuninzi beSulforaphane bumalunga ne-1.3 g/cm³.
Iipropati zeMichiza
1. Ulwakhiwo lweMichiza:
- Igama lekhemikhali ye-Sulforaphane yi-1-isothiocyanate-4-methylsulfonylbutane, ifomula yayo ye-molecular yi-C6H11NOS2, kunye nesisindo sayo se-molecular yi-177.29 g / mol.
- Isakhiwo sayo siqulethe i-isothiocyanate (-N = C = S) iqela kunye ne-methylsulfonyl (-SO2CH3) iqela.
2. Uzinzo:
-I-Sulforaphane izinzile phantsi kweemeko ezingathathi hlangothi kwaye zibuthathaka, kodwa zibola ngokulula phantsi kweemeko ezinamandla kunye ne-alkaline.
- Ubuthathaka kukukhanya kunye nobushushu, ukuvezwa ixesha elide ekukhanyeni kunye namaqondo obushushu aphezulu kunokubangela ukuthotywa kwawo.
3. Ukuphinda kusebenze:
-I-Sulforaphane ine-reactivity ephezulu yeekhemikhali kwaye inokusabela ngeendidi zeamolekyuli zebhayoloji.
- Iqela layo le-isothiocyanate linokudibanisa ngokudibeneyo kunye ne-sulfhydryl (-SH) kunye namaqela e-amino (-NH2) ukwenza iimveliso zokongeza ezizinzile.
4. I-Antioxidant:
-I-Sulforaphane ineepropathi ezinamandla ze-antioxidant, ezikwaziyo ukuthothisa ii-radicals zasimahla kunye nokunciphisa umonakalo owenziwe yi-oxidative kwiiseli.
5. Umsebenzi webhayoloji:
-I-Sulforaphane inemisebenzi eyahlukeneyo yezinto eziphilayo, kuquka ukulwa nomhlaza, ukuchasana nokuvuvukala, ukuchithwa kwe-detoxification kunye neuroprotection.
Umthombo weSulforaphane
Imithombo ephambili
1. Brokholi:
I-Broccoli Sprouts: I-Broccoli sprouts yenye yezona zinto ziphezulu zeSulforaphane. Uphando lubonisa ukuba umxholo we-Sulforaphane kwihlumela le-broccoli uphindaphindeka izihlandlo ezininzi kunoko kwi-broccoli evuthiweyo.
- I-Broccoli evuthiweyo: Nangona umxholo we-Sulforaphane ungekho phezulu njenge-broccoli ihluma, i-broccoli ekhulile isengumthombo obalulekileyo we-Sulforaphane.
2. Ikholifulawa:
- ICauliflower ikwayimifuno yecruciferous etyebileyo kwisulforaphane, ngakumbi amagqabi ayo amancinci.
3. Ikhaphetshu:
- Ikhaphetshu, kubandakanywa nekhaphetshu ebomvu neluhlaza, iqulethe izixa ezithile zeSulforaphane.
4. Imifuno yeMustard:
- Imifuno yeMustard ikwangumthombo olungileyo weSulforaphane, ngakumbi amahlumela awo amancinci.
5. Kale:
- I-Kale yimifuno ye-cruciferous enezondlo eziqulethe i-Sulforaphane.
6. Iradish:
- Radish kunye nezihluma zayo zikwaneSulforaphane.
7. Eminye imifuno yecruciferous:
- Eminye imifuno ye-cruciferous efana neBrussels Sprouts, Turnip, Chinese Kale, njl. Kwakhona iqulethe inani elithile le-Sulforaphane.
Inkqubo yokuvelisa i-sulforaphane
I-Sulforaphane ayikho ngokuthe ngqo kule mifuno, kodwa kwifom ye-precursor, i-glucose isothiocyanate (glucoraphanin). Xa ezi mifuno zisikwa, zihlafunwa okanye zaphukile, iindonga zeseli ziyaqhekeka, zikhuphe i-enzyme ebizwa ngokuba yi-myrosinase. Le enzyme iguqula i-glucose isothiocyanate ibe yiSulforaphane.
Izindululo zokwandisa ukuthatha kwakho iSulforaphane
I-1.Izihluma ezidliwayo: Khetha ukutya iindawo ezihlumayo ezifana nezihluma ze-broccoli kuba ziqulethe umxholo ophezulu we-Sulforaphane.
2. Ukupheka ukukhanya: Gwema ukugqithisa, njengoko ukushisa okuphezulu kuya kutshabalalisa i-glucosinosidase kunye nokunciphisa ukuveliswa kweSulforaphane. I-steaming encinci yeyona ndlela yokupheka engcono.
3. Ukutya okuluhlaza: Ukutya okuluhlaza kwemifuno ye-cruciferous kunokugcina i-enzyme ye-glucosinolate ukuya kwinqanaba eliphezulu kwaye ikhuthaze ukuveliswa kwe-Sulforaphane.
4. Yongeza i-mustard: Ukuba ufuna ukupheka, unokongeza i-mustard ngaphambi kokutya, kuba isardadi iqukethe i-glucosinolates, enokukunceda ukuvelisa i-Sulforaphane.
Ziziphi iiNzuzo zeSulforaphane?
I-Sulforaphane ineenzuzo ezahlukeneyo zempilo, nazi ezona ziphumo ziphambili kunye nezibonelelo zeSulforaphane:
1. I-Antioxidant:
I-Neutralizing Free Radicals: I-Sulforaphane ineepropathi ezinamandla ze-antioxidant ezenza i-radicals yasimahla kwaye inciphise umonakalo kwiiseli obangelwa kuxinzelelo lwe-oxidative.
- Sebenzisa i-antioxidant enzymes: Ukuphucula amandla e-antioxidant yeeseli ngokuvula inkqubo ye-antioxidant ye-enzyme emzimbeni, njenge-glutathione peroxidase kunye ne-superoxide dismutase.
2. Ukuchasana nomhlaza:
- Ukuthintela ukukhula kweeseli zomhlaza: I-Sulforaphane inokuthintela ukukhula kunye nokwanda kweeseli zomhlaza ezahlukeneyo, kubandakanya umhlaza webele, umhlaza wesifo seprotate, kunye nomhlaza wekoloni.
-Yenza i-apoptosis: Ukunciphisa izinga lokusinda kweeseli zomhlaza ngokubangela i-apoptosis (ukufa kweseli ecwangcisiweyo) yeeseli zomhlaza.
- Ukuthintela i-tumor angiogenesis: Ukuthintela ukubunjwa kwemithambo yegazi emitsha kwi-tumor, ukunciphisa ukunikezelwa kwezondlo kwi-tumor, ngaloo ndlela kuthintela ukukhula kwe-tumor.
3. Anti-ukudumba:
- Ukunciphisa i-Inflammatory Response: I-Sulforaphane inezixhobo ezichasayo, ezinokuthintela ukukhululwa kwabalamli abavuthayo kunye nokunciphisa iimpendulo ezivuthayo.
- Khusela i-Tissue: Ikhusela izicubu kumonakalo obangelwa ukuvuvukala ngokunciphisa ukuvuvukala.
4. Ukuphelisa ubutyhefu:
- Ukukhuthaza ukuveliswa kwe-enzymes ye-detoxification: I-Sulforaphane inokuvula inkqubo ye-enzyme ye-detoxification emzimbeni, njenge-glutathione-S-transferase, ukunceda ukuphelisa izinto ezinobungozi kunye ne-toxins emzimbeni.
- Ukuphucula ukusebenza kwesibindi: Khusela impilo yesibindi ngokukhuthaza umsebenzi wokukhupha isibindi.
5. Ukhuseleko lwemithambo-luvo:
- Khusela iiseli zeNerve: I-Sulforaphane ineempembelelo ze-neuroprotective kwaye iyakwazi ukukhusela iiseli ze-nerve emonakalweni ngoxinzelelo lwe-oxidative kunye nokudumba.
- Ukuthintela izifo ze-Neurodeergenerative: Uphando lucebisa ukuba i-Sulforaphane inokunceda ukukhusela kunye nokucothisa ukuqhubela phambili kwezifo ze-neurodeergenerative ezifana nesifo se-Alzheimer kunye nesifo sika-Parkinson.
6. Impilo yentliziyo:
-NCIPHA UXINEZELEKO LWEGAZI: I-Sulforaphane inceda ukuthoba uxinzelelo lwegazi kunye nokuphucula impilo yentliziyo.
- Iyanciphisa i-arteriosclerosis: Ngokusebenzisa i-antioxidant kunye ne-anti-inflammatory effects, i-Sulforaphane inokunciphisa umngcipheko we-arteriosclerosis kunye nokukhusela inkqubo ye-cardiovascular system.
7. I-Antibacterial kunye ne-Antiviral:
- I-Pathogen Inhibition: I-Sulforaphane ine-antibacterial kunye ne-antiviral properties ezivimbela ukukhula kunye nokuveliswa kweentlobo ezahlukeneyo ze-pathogens.
- Ukuphucula ukusebenza kwe-immune: Ukuphucula amandla omzimba okulwa nosulelo ngokunyusa umsebenzi we-immune system.
Yintoni Izicelo ZeSulforaphane?
IZOngezo ZOKUTYA:
I-1.Izongezelelo ze-Antioxidant: I-Sulforaphane isoloko isetyenziselwa izongezo ze-antioxidant ukunceda ukunciphisa i-radicals yamahhala kunye nokunciphisa umonakalo woxinzelelo lwe-oxidative emzimbeni.
I-2.I-Anti-cancer supplement: Isetyenziswa kwizongezo ezichasene nomhlaza ukunceda ukuthintela ukukhula kunye nokwanda kweeseli zomhlaza kunye nokuphucula amandla omzimba wokulwa nomhlaza.
UKUTYA OKUSEBENZAYO:
I-1.UKUTYA OKUNEMPILO: I-Sulforaphane inokongezwa kukutya okusebenzayo okufana neziselo zempilo kunye nemivalo yesondlo ukubonelela ngezibonelelo zempilo ezongezelelweyo.
I-2.I-Vegetable Extract: Njengesicatshulwa semifuno ye-cruciferous, isetyenziswa ngokubanzi kwizidlo zezempilo ezahlukeneyo.
IIMVELISO ZOKUKHATHALELA ULUSU:
I-1.Imveliso yokunakekelwa kwesikhumba ye-Antioxidant: I-Sulforaphane isetyenziselwa kwiimveliso zokunakekelwa kwe-antioxidant ukuze zincede ukunciphisa i-radicals yamahhala kunye nokunciphisa umonakalo we-oxidative eluswini.
I-2.Imveliso yokunakekelwa kwesikhumba: Isetyenziswe kwiimveliso zokunakekelwa kwesikhumba ezichasayo ekuncedeni ukunciphisa impendulo yokuvuvukala kwesikhumba kunye nokukhusela impilo yesikhumba.
Imibuzo eNxulumeneyo onokuthi ubenomdla kuyo:
Zithini iziphumo ebezingalindelekangasulforaphane?
I-Sulforaphane yindalo ye-organosulfur ikhompawundi efumaneka ikakhulu kwimifuno ye-cruciferous efana ne-broccoli, i-cauliflower, i-kale, kunye nemifuno yemostade. Nangona i-Sulforaphane inezibonelelo ezininzi zempilo, kwezinye iimeko, ezinye iziphumo ebezingalindelekanga zinokwenzeka. Oku kulandelayo ziziphumo ebezingalindelekanga kunye nezilumkiso zeSulforaphane:
1. Ukungakhululeki kwesisu:
Ukuqunjelwa kunye neGesi: Abanye abantu banokuba neempawu zokuqunjelwa kunye negesi emva kokuthatha idosi ephezulu yeSulforaphane.
Urhudo: Idosi ephezulu yeSulforaphane inokubangela urhudo, ngakumbi kubantu ababuthathaka.
Iintlungu zesisu kunye neNausea: Abanye abantu banokufumana iintlungu zesisu kunye nesicaphucaphu emva kokusela iSulforaphane.
2. Ukwalana:
- Iimpendulo zolusu: Inani elincinci labantu linokuba ne-allergies kwi-Sulforaphane, ebonakalisa njengokurhawuzelelwa, irhashalala ebomvu, okanye i-hives.
-Ingxaki yokuphefumla: Kunqabile, iSulforaphane inokubangela ukuchasana okunzulu, okufana nobunzima bokuphefumla okanye ukudumba komqala. Ukuba ezi mpawu ziyenzeka, funa unyango ngokukhawuleza.
3. Impembelelo kumsebenzi wedlala lengqula:
- I-Goiter: Imifuno ye-Cruciferous iqulethe izinto zendalo ze-thyroid-inhibiting (ezifana ne-thiocyanates). Ukusetyenziswa kwexesha elide lemali eninzi kunokuchaphazela umsebenzi we-thyroid kwaye kukhokelela ekwandiseni i-thyroid (goiter).
- I-Hypothyroidism: Kwiimeko ezinqabileyo, ixesha elide, ukuthathwa okuphezulu kwe-Sulforaphane kunokuchaphazela i-hormone ye-thyroid synthesis, ekhokelela kwi-hypothyroidism.
4. Ukusebenzisana kweziyobisi:
- I-Anticoagulants: I-Sulforaphane inokuchaphazela ukusebenza kwe-anticoagulants (efana ne-warfarin) kunye nokunyusa umngcipheko wokuphuma kwegazi.
- Amanye Amachiza: I-Sulforaphane inokunxibelelana namanye amachiza, echaphazela imetabolism kunye nokusebenza kwawo. Ukuba uthatha iSulforaphane ngelixa uthatha amayeza, kuya kufuneka udibane nogqirha wakho.
Amanqaku:
1. Ukuthathwa okuphakathi:
- Control Dosage: NangonaSulforaphaneineenzuzo ezininzi zempilo, kufuneka ithathwe ngokumodareyitha ukuphepha ukugqithisa. Kuyacetyiswa ngokubanzi ukufumana i-Sulforaphane ngokusetyenziswa kwemifuno e-cruciferous kunokuthembela kwizongezo zedosi ephezulu.
2. Umahluko womntu ngamnye:
- Abantu abanovelwano: Abanye abantu banokuba novelwano ngakumbi kwiSulforaphane kwaye bathambekele kwiziphumo ebezingalindelekanga. Eli qela labantu kufuneka lihlawule ngokukodwa ekuthatheni kwabo kwaye lenze uhlengahlengiso ngexesha elifanelekileyo xa kwenzeka ukungahambi kakuhle.
3. Abasetyhini abakhulelweyo nabancancisayo:
- SEBENZISA NGOKULUMKO: Abasetyhini abakhulelweyo nabancancisayo kufuneka balumke xa befaka i-Sulforaphane, ngokukhethekileyo phantsi kolawulo lukagqirha.
4. Izigulana ezinezifo ezingapheliyo:
- BONISANA NOGQIRHA: Izigulane ezineemeko zonyango ezingapheliyo (ezifana nesifo se-thyroid, isifo sesibindi, okanye isifo sezintso) kufuneka udibane nodokotela ngaphambi kokungena kwi-Sulforaphane ukuqinisekisa ukhuseleko.
Ndingathatha ixesha elingakanani isulforaphane?
I-Dietary Intake: Ikhuselekile ekusebenziseni ixesha elide njengenxalenye yokutya okunokulinganisela okucebile kwimifuno ye-cruciferous.
Ukutya okongeziweyo: Ngokuqhelekileyo kukhuselekile ukusetyenziswa kwexesha elifutshane; ukusetyenziswa kwexesha elide kufuneka kukhokelwe yingcali yezempilo.
Yintoni eyenziwa ngumhlazasulforaphanethintela?
I-Sulforaphane inoluhlu olubanzi lweepropathi ezichasene nomhlaza kwaye inokuthintela kwaye inqanda iintlobo ezininzi zomhlaza, kubandakanya ibele, i-prostate, ikholoni, imiphunga, isisu, isinyi kunye nomhlaza wolusu. Iindlela zayo eziphambili zibandakanya ukuvimbela ukukhula kunye nokwanda kweeseli zomhlaza, ukunyusa i-apoptosis, inhibiting tumor angiogenesis, i-antioxidant, i-anti-inflammatory kunye ne-detoxification, njl. Ngokutya imifuno ye-sulforaphane ecebileyo ye-cruciferous, umngcipheko weentlobo ezininzi zomhlaza unokunciphisa ngokufanelekileyo.
Ngaba i-sulforaphane iyayonyusa i-estrogen?
Uphando lwangoku lubonisa ukuba i-Sulforaphane inokuchaphazela imetabolism kunye neziphumo ze-estrogen ngeendlela ezininzi, kubandakanya ukukhuthaza ukuchithwa kwe-estrogen, ukulungelelanisa iindlela ze-estrogen metabolic, inhibiting estrogen receptors, kunye nokunciphisa ukubonakaliswa kwe-estrogen.
Ixesha lokuposa: Sep-19-2024
