Abaphandi bafumene unyango olutsha olunokubakho kwi-Alzheimer's disease ngohlobo lweEGCG, ikhompawundi efumaneka kwiti eluhlaza. Uphononongo olupapashwe kwiJenali yeBiological Chemistry yafumanisa ukubaEGCGinokuphazamisa ukubunjwa kwee-amyloid plaques, eziluphawu lwesifo se-Alzheimer. Abaphandi baqhube iimvavanyo kwiimpuku kwaye bafumanisa ukubaEGCGyanciphisa ukuveliswa kweeprotheni ze-amyloid beta, ezaziwa ngokuqokelela kwaye zenze amacwecwe ebuchotsheni bezigulane ze-Alzheimer. Esi siphumo sicebisa ukubaEGCGinokuba ngumgqatswa othembisayo wokuphuhliswa konyango olutsha lwe-Alzheimer's disease.
Inzululwazi ngasemvaEGCG: Ukuphonononga iiNzuzo zempilo kunye nezicelo ezinokuthi zibe kho :
Uphononongo lukwafumanise ukubaEGCGinokunceda ukukhusela iiseli zengqondo kwimiphumo eyityhefu ye-amyloid beta proteins. Oku kubalulekile kuba ukufa kweeseli zengqondo ngoyena nobangela wokuqhubekeka kwesifo sika-Alzheimer. Ngokuthintela iziphumo eziyityhefu ze-amyloid beta proteins,EGCGinokucothisa ukuqhubeka kwesi sifo kwaye igcine umsebenzi wokuqonda kwizigulana.
Ukongeza kwiingenelo ezinokuthi zibekho kwisifo sika-Alzheimer,EGCGiye yaphononongwa ngeempawu zayo zokulwa nomhlaza. Uphando luye lwabonisa ukubaEGCGinokuthintela ukukhula kweeseli zomhlaza kwaye ibangele i-apoptosis, okanye ukufa kweeseli ezicwangcisiweyo, kwiiseli zomhlaza. Oku kuthetha ukubaEGCGinokuba sisixhobo esixabisekileyo kuphuhliso lonyango olutsha lomhlaza.
Ngaphezu koko,EGCGifunyenwe inezinto ezichasayo kunye ne-antioxidant, enokuyenza ibe luncedo kuluhlu lweemeko zempilo. Uphando luye lwabonisa ukubaEGCGkunokunceda ukunciphisa ukuvuvukala emzimbeni kunye nokukhusela iiseli kumonakalo we-oxidative. Oku kunokuba nefuthe kwiimeko ezifana nesifo senhliziyo, isifo seswekile, kunye nesifo samathambo.
Ukufunyanwa kweEGCG's iinzuzo ezinokuthi zibe khona kwi-Alzheimer's disease kunye ne-anti-cancer eyaziwayo, anti-ukudumba, kunye ne-antioxidant iipropathi ziyenza ibe yindawo enika umdla yophando. Uphononongo olongezelelweyo luya kufuneka ukuqonda ngokupheleleyo iindlela zokusebenza zeEGCGkunye nokumisela amandla ayo njenge-arhente yonyango kwiimeko ezahlukeneyo zempilo. Nangona kunjalo, iziphumo ukuza kuthi ga ngoku zibonisa ukubaEGCGinokubamba isithembiso sophuhliso lonyango olutsha lwe-Alzheimer's kunye nezinye iimeko zempilo.
Ixesha lokuposa: Jul-29-2024
