IHydroxypropyl Beta Cyclodextrin CAS 128446-35-5 hydroxypropyl-β-cyclodextrin
Ingcaciso yeMveliso
I-Hydroxypropyl beta-cyclodextrin yikhompawundi esetyenziswa ngokuqhelekileyo njenge-adjuvant kwiinkqubo zokuhanjiswa kweziyobisi.Kwicandelo lezonyango, inezi ziphumo zilandelayo:
Ukuphucula ukunyibilika kweziyobisi: I-Hydroxypropyl β-cyclodextrin inokwenza ii-complexes ezifakwe kunye nezinye izidakamizwa ezingenayo i-insoluble, ukuphucula ukunyibilika kweziyobisi kunye nokuzinza, kunye nokwandisa ukuxutywa kweziyobisi kunye ne-bioavailability.
Ukuphucula ukuzinza kweziyobisi: I-Hydroxypropyl β-cyclodextrin inokukhusela amanye amachiza achaphazeleka ngokulula kukukhanya, ukushisa, i-oksijini kunye nezinye izinto, ukwandisa ukuzinza kunye nobomi beshelufu yamachiza.
Ukuphucula incasa: I-Hydroxypropyl β-cyclodextrin inokufihla ezinye izinto ezimbi ezinjengobukrakra kunye nobumuncu bechiza, iphucule incasa, kwaye yenze ukuba iyeza libe lula ukulamkela kunye nokusetyenziswa.
Ukunciphisa ubuthi: I-Hydroxypropyl β-cyclodextrin inokuthotywa yinkqubo ye-enzyme emzimbeni kwizinto ezingenabungozi ezinokuthi zikhutshwe, ezinokunciphisa i-toxic and side effects of the drug kumzimba womntu.Ukongeza kwisicelo kwintsimi yeyeza, i-hydroxypropyl β-cyclodextrin isetyenziselwa ngokubanzi ukutya, izimonyo kunye nezinye iinkalo zokuphucula ukunyibilika, ukuzinza kunye nokunambitha.
Ukutya
Ukwenza mhlophe
Iipilisi
Ukwakhiwa Kwezihlunu
Izongezo zokutya
Umsebenzi
I-Hydroxypropyl β-cyclodextrin yi-molecule ye-sugar cyclic kunye ne-agent e-soluble ye-molecular encapsulating agent.Inemisebenzi eyahlukeneyo, kuquka:
I-1.I-Solubilization: I-Hydroxypropyl β-cyclodextrin inokuphucula ukunyibilika kwamachiza angabonakaliyo kunye nokukhuthaza ukuchithwa kwawo emanzini, ngaloo ndlela kuphuculwe i-bioavailability yabo.
I-2.Uzinzo oluphuculweyo: I-Hydroxypropyl β-cyclodextrin inokukhusela iimolekyuli zeziyobisi ezinobuthathaka emonakalweni ngezinto ezisingqongileyo ezifana nokukhanya, i-oksijini, kunye nobushushu, kunye nokuphucula ukuzinza kweziyobisi kunye nobomi beshelufu.
I-3.I-Encapsulation: I-Hydroxypropyl β-cyclodextrin inokufakela iimolekyuli ezingazinzanga, eziguquguqukayo, okanye ezingathandekiyo ngaphakathi kwayo nge-molecular encapsulation, ngaloo ndlela iphucula ukuzinza kwayo kunye namava omsebenzisi.
I-4.I-Taste-masking: I-Hydroxypropyl beta-cyclodextrin inokugqoka iimolekyuli zamachiza ezikrakra, ezihlabayo okanye ezingathandekiyo ukuphucula incasa yeziyobisi kunye nokwamkelwa kwesigulane.
I-5.Ukuhanjiswa kweziyobisi: I-Hydroxypropyl β-cyclodextrin inokuphucula ukuxutywa kunye nokusasazwa kweziyobisi emzimbeni ngokunyusa ukunyibilika kwamanzi kunye nokuzinza kwee-molecule zamachiza, ngaloo ndlela kuphuculwe ukusebenza kweziyobisi.
Isicelo
I-Hydroxypropyl β-cyclodextrin yi-agent ye-molecular encapsulating agent enokuphucula ukunyibilika, ukuzinza, ukunambitha kunye nokuhanjiswa kweziyobisi, kwaye isetyenziswa ngokubanzi kumayeza, ukutya, izimonyo kunye nezinye iinkalo.
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